Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.51 |
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL716007 | 0.86 | NPC1 (0.56) | NPC1RAB9ASYKCTSK | |
| SCHEMBL17042179 | 0.83 | NPC1 (0.53) | NPC1RAB9ASYKALDH1A1SMN1; SMN2 | |
| SCHEMBL9571959 | 0.79 | NPC1 (0.62) | NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL1349741 | 0.78 | NPC1 (0.57) | NPC1RAB9AKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL32665608 | 0.77 | NPC1 (0.53) | NPC1RAB9AKDM4EMEN1MAPT | |
| SCHEMBL28102925 | 0.76 | NPC1 (0.56) | NPC1RAB9AKDM4EMEN1MAPT | |
| SCHEMBL18490885 | 0.76 | PPARA (0.54) | NPC1RAB9AMEN1KMT2ASYK | |
| SCHEMBL8736454 | 0.76 | NPC1 (0.55) | NPC1RAB9AMAPTCTSKALDH1A1 | |
| SCHEMBL7122013 | 0.76 | NPC1 (0.59) | NPC1RAB9AALDH1A1SMN1; SMN2HDAC3 | |
| SCHEMBL29429363 | 0.75 | NPC1 (0.62) | NPC1RAB9AALDH1A1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130177851-A1 | PHOTORESIST COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-07-11 | — | — | US | disclosed |
| US-20130177851-A1 | PHOTORESIST COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-07-11 | — | — | US | disclosed |