Sugi Predict

Sugi Predict / Compounds / SCHEMBL716007

SCHEMBL716007

SCHEMBL716007

CC(C)(C)OC(=O)NOCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 4/20 0.56
▸ RAB9A P51151 4/20 0.56
▸ CA12 O43570 1/20 0.52
▸ CA1 P00915 1/20 0.52
▸ CA7 P43166 1/20 0.52
▸ CA14 Q9ULX7 1/20 0.52
▸ PPARA Q07869 2/20 0.51
▸ SYK P43405 1/20 0.51
▸ AKT1 P31749 2/20 0.50
▸ CTSS P25774 5/20 0.48
▸ CTSL P07711 3/20 0.48
▸ CTSB P07858 3/20 0.48
▸ ATM Q13315 1/20 0.48
▸ IDO1 P14902 1/20 0.47
▸ PPARG P37231 1/20 0.46
▸ CTSK P43235 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32665608 0.90 NPC1 (0.53) NPC1RAB9APPARG
SCHEMBL18490885 0.89 PPARA (0.54) NPC1RAB9ACA12CA1CA7
SCHEMBL17042179 0.87 NPC1 (0.53) NPC1RAB9ACA12CA1CA7
SCHEMBL32665348 0.87 MIF (0.48) NPC1RAB9APPARASYKCTSS
SCHEMBL32665594 0.87 MAOB (0.51) —
SCHEMBL15096046 0.86 NPC1 (0.51) NPC1RAB9ASYKCTSK
SCHEMBL16588058 0.85 RAB9A (0.44) NPC1RAB9ACA12CA1CA7
SCHEMBL18500725 0.85 SYK (0.51) NPC1RAB9ACA12CA1CA7
SCHEMBL4399149 0.85 MRGPRX4 (0.50) NPC1RAB9A
SCHEMBL32665616 0.85 PTGER1 (0.46) CA12CA1CA7CA14PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250101261-A1 CHEMICAL MECHANICAL PLANARIZATION SLURRY PROCESSING TECHNIQUES AND SYSTEMS AND METHODS FOR POLISHING SUBSTRATE USING THE SAME ARACA, INC. 2025-03-27 — — US claimed
EP-4449481-A1 CHEMICAL MECHANICAL PLANARIZATION SLURRY PROCESSING TECHNIQUES AND SYSTEMS AND METHODS FOR POLISHING SUBSTRATE USING THE SAME Araca, Inc. (US) 2024-10-23 — — EP claimed
WO-2023149925-A1 CHEMICAL MECHANICAL PLANARIZATION SLURRY PROCESSING TECHNIQUES AND SYSTEMS AND METHODS FOR POLISHING SUBSTRATE USING THE SAME ARACA, INC. (US) 2023-08-10 — — WO claimed
US-20130274475-A1 BETA-LACTAMASE INHIBITORS MERCK SHARP & DOHME (US) 2013-10-17 — — US claimed
EP-2231667-B1 BETA-LACTAMASE INHIBITORS MERCK SHARP & DOHME (US) 2013-09-04 — — EP claimed
US-20120053350-A1 PREPARATION OF ALKYL ESTERS OF N-PROTECTED OXO-AZACYCLOALKYLCARBOXYLIC ACIDS MERCK SHARP & DOHME CORP. 2012-03-01 — — US claimed
WO-2010126820-A2 PREPARATION OF ALKYL ESTERS OF N-PROTECTED OXO-AZACYCLOALKYLCARBOXYLIC ACIDS MERCK SHARP & DOHME CORP. (US) 2010-11-04 — — WO claimed
EP-2231667-A2 BETA-LACTAMASE INHIBITORS Merck Sharp & Dohme Corp. (US) 2010-09-29 — — EP claimed
WO-2009091856-A2 BETA-LACTAMASE INHIBITORS MERCK & CO., INC. (US) 2009-07-23 — — WO claimed
US-6319310-B1 FOR ACOUSTIC INK JET PRINTING; TRANSPARENCY, GLOSS, CREASE RESISTANCE XEROX CORPORATION 2001-11-20 — — US claimed
US-6288141-B1 Ink compositions XEROX CORPORATION 2001-09-11 — — US claimed
US-6045607-A FIRST AND SECOND SOLID CARBAMATES WITH A DISSIMILAR MELTING POINTS; LIGHTFASTNESS COMPONENT; A LIGHTFASTNESS ANTIOXIDANTS, AND A COLORANT; USEFUL FOR ACOUSTIC INK PRINTING XEROX CORPORATION (US) 2000-04-04 — — US claimed
US-20260069726-A1 ZWITTERIONIC COMPOUNDS AND USES THEREOF UNIV SASKATCHEWAN (CA) 2026-03-12 — — US disclosed
WO-2025226938-A1 COMBINATIONS OF NEOENACTINS WITH ANTI-FUNGAL AGENTS WITH ENHANCED ANTI-FUNGAL ACTIVITY Hsiri Therapeutics, Inc. (US) 2025-10-30 — — WO disclosed
US-12448545-B2 Silicon carbide (SIC) wafer polishing with slurry formulation and process ARACA, INC. (US) 2025-10-21 — — US disclosed
US-12344597-B2 Alkoxy-substituted pyridinyl derivatives as LPA1 receptor antagonists and their use in the treatment of fibrosis IDORSIA PHARMACEUTICALS LTD (CH) 2025-07-01 — — US disclosed
EP-0531976-A1 Heteroaryl derivatives of monocyclic beta-lactam antibiotics E.R. SQUIBB & SONS, INC. (US) 1993-03-17 — — EP disclosed
EP-0484881-A2 Heteroaroyl derivatives of monocyclic beta-lactam antibiotics E.R. SQUIBB & SONS, INC. (US) 1992-05-13 — — EP disclosed
US-5066658-A Enzyme Inhibitors; Bronchodilators; Antiinflammatory Agents ORTHO PHARMACEUTICAL CORPORATION (US) 1991-11-19 — — US disclosed
US-4987253-A Method for the synthesis of desferrioxamine B and analogs thereof UNIVERSITY OF FLORIDA (US) 1991-01-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344597-B2 Alkoxy-substituted pyridinyl derivatives as LPA1 receptor antagonists and their use in the treatment of fibrosis LPAR1, LPAR3, LPAR2 NPC1 838/4885RAB9A 2340/4885CA12 4876/4885
US-20120053350-A1 PREPARATION OF ALKYL ESTERS OF N-PROTECTED OXO-AZACYCLOALKYLCARBOXYLIC ACIDS SULT1A1, SULT1E1, PGD NPC1 3829/4885RAB9A 3451/4885CA12 3430/4885
US-20130274475-A1 BETA-LACTAMASE INHIBITORS MGAM, RPIA, XDH NPC1 2510/4885RAB9A 770/4885CA12 3963/4885
US-20260069726-A1 ZWITTERIONIC COMPOUNDS AND USES THEREOF CA13, SLCO2B1, SLCO2A1 NPC1 192/4885RAB9A 497/4885CA12 7/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.