Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10155722 | 0.78 | BACE1 (0.59) | BACE1APP | |
| SCHEMBL10154968 | 0.77 | BACE1 (0.56) | BACE1APP | |
| SCHEMBL10156225 | 0.76 | BACE1 (0.66) | BACE1APP | |
| SCHEMBL10154673 | 0.74 | BACE1 (0.64) | BACE1APP | |
| SCHEMBL17635522 | 0.74 | BACE1 (0.62) | BACE1APP | |
| SCHEMBL10154813 | 0.73 | BACE1 (0.61) | BACE1APP | |
| SCHEMBL10155489 | 0.73 | BACE1 (0.58) | BACE1 | |
| SCHEMBL10157601 | 0.73 | BACE1 (0.62) | BACE1APP | |
| SCHEMBL10156547 | 0.73 | BACE1 (0.62) | BACE1APP | |
| SCHEMBL10154814 | 0.72 | BACE1 (0.76) | BACE1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2612854-A1 | Aminothiazolidine and aminotetrahydrothiazepine derivatives as BACE 1 inhibitors | Shionogi&Co., Ltd. (JP) | 2013-07-10 | — | — | EP | disclosed |