Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | PPME1 | Q9Y570 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5963538 | 0.78 | ELANE (0.51) | ELANEMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7779914 | 0.77 | ELANE (0.52) | ELANEMEN1KMT2AABCB1ATM | |
| SCHEMBL9037297 | 0.77 | ELANE (0.52) | ELANEMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9037293 | 0.77 | ELANE (0.52) | ELANEMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9037300 | 0.77 | ELANE (0.52) | ELANEMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL5964086 | 0.75 | ELANE (0.49) | ELANEMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL15304960 | 0.74 | ELANE (0.48) | ELANEMEN1KMT2AALDH1A1ABCB1 | |
| SCHEMBL15096382 | 0.70 | ELANE (0.49) | ELANE | |
| SCHEMBL6409371 | 0.69 | ELANE (0.51) | ELANEMEN1KMT2AABCB1 | |
| SCHEMBL3076587 | 0.69 | ELANE (0.51) | ELANEMEN1KMT2AABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948669-B1 | NEW METHODS FOR THE PREPARATION OF TAXANES USING CHIRAL AUXILIARIES | ACCORD HEALTHCARE INC (CA) | 2013-07-10 | — | — | EP | disclosed |