Apaflurane

Apaflurane

SCHEMBL1509786

FC(C(F)(F)F)C(F)(F)F.FC(F)CC(F)(F)F

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18764 0.87
SCHEMBL7158922 0.84
SCHEMBL8712085 0.83
Fluoride SCHEMBL6364058 0.83
Ammonia Solution, Strong SCHEMBL28412649 0.83
Fluoride Ion SCHEMBL6364056 0.80
Fluoromethane SCHEMBL28346221 0.80
SCHEMBL6057879 0.80
SCHEMBL4163136 0.79 ALDH1A1 (0.33)
SCHEMBL7938550 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2292683-B1 Expanded and Extruded Thermoplastic Foams made wth Methyl Formate-Based Blowing Agents PACTIV CORP (US) 2012-12-12 EP disclosed
EP-1317406-B2 PROCESS FOR OBTAINING A PURIFIED HYDROFLUOROALKANE SOLVAY (BE) 2012-11-14 EP disclosed
EP-2292683-A1 Expanded and Extruded Thermoplastic Foams made wth Methyl Formate-Based Blowing Agents Pactiv Corporation (US) 2011-03-09 EP disclosed
US-20100181186-A1 Process for obtaining a purified hydrofluoroalkane SOLVAY FLUOR GMBH (DE) 2010-07-22 US disclosed
US-7750195-B2 Process for obtaining a purified hydrofluoroalkane SOLVAY S.A. (BE) 2010-07-06 US disclosed
EP-2170789-A1 PROCESS FOR OBTAINING A PURIFIED HYDROFLUOROALKANE Solvay Fluor GmbH (DE) 2010-04-07 EP disclosed
US-20090099394-A1 PROCESS FOR OBTAINING A PURIFIED HYDROFLUOROALKANE SOLVAY S.A. (BE) 2009-04-16 US disclosed
WO-2009013198-A1 PROCESS FOR OBTAINING A PURIFIED HYDROFLUOROALKANE SOLVAY FLUOR GMBH (DE) 2009-01-29 WO disclosed
US-7468467-B2 Process for obtaining a purified hydrofluoroalkane SOLVAY S.A. (BE) 2008-12-23 US disclosed
EP-1985601-A2 Process for obtaining a purified hydrofluoroalkane SOLVAY (Société Anonyme) (BE) 2008-10-29 EP disclosed
EP-1317406-B1 PROCESS FOR OBTAINING A PURIFIED HYDROFLUOROALKANE SOLVAY (BE) 2008-08-20 EP disclosed
US-20070112231-A1 Process for obtaining a purified hydrofluoroalkane SOLVAY S.A. (BE) 2007-05-17 US disclosed
US-7179949-B2 Process for obtaining a purified hydrofluoroalkane SOLVAY (SOCIETE ANONYME) (BE) 2007-02-20 US disclosed
US-20060052466-A1 Expanded and extruded thermoplastic foams made with methyl formate-based blowing agents PACTIV CORPORATION 2006-03-09 US disclosed
US-20040030204-A1 Process for obtaining a purified hydrofluoroalkane SOLVAY (SOCIETE ANONYME) (BE) 2004-02-12 US disclosed
EP-1317406-A1 PROCESS FOR OBTAINING A PURIFIED HYDROFLUOROALKANE SOLVAY (Société Anonyme) (BE) 2003-06-11 EP disclosed
WO-2002012153-A1 PROCESS FOR OBTAINING A PURIFIED HYDROFLUOROALKANE Solvay (Société Anonyme) (BE) 2002-02-14 WO disclosed