Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 16/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17548633 | 0.84 | MEN1 (0.56) | MEN1NPC1POLBKMT2ACNR1 | |
| SCHEMBL15099320 | 0.76 | CNR1 (0.72) | CNR1CNR2 | |
| SCHEMBL17548553 | 0.68 | CNR1 (0.57) | MEN1NPC1POLBKMT2ACNR1 | |
| SCHEMBL16362225 | 0.66 | CNR1 (0.69) | CNR1CNR2 | |
| SCHEMBL20408186 | 0.66 | ALDH1A1 (0.48) | NPC1LMNAMAPTALDH1A1HPGD | |
| SCHEMBL15094476 | 0.64 | CNR1 (0.91) | CNR1CNR2 | |
| SCHEMBL20394666 | 0.64 | CNR1 (0.95) | CNR1CNR2 | |
| SCHEMBL18288173 | 0.64 | MEN1 (1.00) | MEN1NPC1POLBKMT2ACNR1 | |
| SCHEMBL15094804 | 0.62 | CNR1 (0.79) | CNR1CNR2 | |
| SCHEMBL9658006 | 0.62 | ALDH1A1 (0.51) | NPC1KMT2ALMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013103967-A1 | ALLOSTERIC MODULATORS OF CB1 CANNABINOID RECEPTORS | NORTHEASTERN UNIVERSITY (US) | 2013-07-11 | — | — | WO | disclosed |