Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COASY | Q13057 | 1/20 | 0.51 |
| ▸ | ICMT | O60725 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 6/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15111493 | 1.00 | COASY (0.51) | COASYICMTEGFRPARP1MAPKAPK2 | |
| SCHEMBL15111488 | 0.86 | COASY (0.48) | COASYPARP1SOS1 | |
| SCHEMBL15111502 | 0.86 | COASY (0.48) | COASYPARP1SOS1 | |
| SCHEMBL15111646 | 0.86 | COASY (0.52) | COASYPARP1GPR139MAOBALDH1A1 | |
| SCHEMBL15111807 | 0.82 | COASY (0.46) | COASYPARP1 | |
| SCHEMBL15111509 | 0.82 | COASY (0.46) | COASYPARP1 | |
| SCHEMBL15111645 | 0.81 | COASY (0.42) | COASYICMTPARP1SOS1 | |
| SCHEMBL15111820 | 0.81 | COASY (0.42) | COASYICMTPARP1SOS1 | |
| SCHEMBL15111477 | 0.81 | COASY (0.42) | COASYICMTPARP1SOS1 | |
| SCHEMBL9589293 | 0.73 | GAA (0.41) | PARP1MAOBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013104577-A1 | BENZIMIDAZOLYL-ACETAMIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | ACESION PHARMA APS (DK) | 2013-07-18 | — | — | WO | disclosed |