Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COASY | Q13057 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 7/20 | 0.39 |
| ▸ | AURKA | O14965 | 3/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | GPR139 | Q6DWJ6 | 3/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15111517 | 0.86 | COASY (0.51) | COASYALDH1A1LMNAHTTPARP1 | |
| SCHEMBL15111493 | 0.86 | COASY (0.51) | COASYALDH1A1LMNAHTTPARP1 | |
| SCHEMBL15111488 | 0.82 | COASY (0.48) | COASYPARP1AURKA | |
| SCHEMBL15111502 | 0.82 | COASY (0.48) | COASYPARP1AURKA | |
| SCHEMBL15111509 | 0.82 | COASY (0.46) | COASYPARP1RPS6KB1PTGES | |
| SCHEMBL15111807 | 0.82 | COASY (0.46) | COASYPARP1RPS6KB1PTGES | |
| SCHEMBL15111645 | 0.79 | COASY (0.42) | COASYPARP1RPS6KB1PTGES | |
| SCHEMBL15111477 | 0.79 | COASY (0.42) | COASYPARP1RPS6KB1PTGES | |
| SCHEMBL15111820 | 0.79 | COASY (0.42) | COASYPARP1RPS6KB1PTGES | |
| SCHEMBL15111647 | 0.71 | GAA (0.42) | ALDH1A1PARP1RPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013104577-A1 | BENZIMIDAZOLYL-ACETAMIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | ACESION PHARMA APS (DK) | 2013-07-18 | — | — | WO | claimed |
| WO-2013104577-A1 | BENZIMIDAZOLYL-ACETAMIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | ACESION PHARMA APS (DK) | 2013-07-18 | — | — | WO | disclosed |