Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.80 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.80 |
| ▸ | TUBB | P07437 | 4/20 | 0.80 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.80 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.80 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.80 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.80 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.80 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.80 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.80 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.80 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.80 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.80 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.80 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.80 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.80 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.80 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.80 |
| ▸ | MEN1 | O00255 | 2/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13661869 | 0.96 | NPC1 (0.79) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13661870 | 0.96 | NPC1 (0.79) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13661876 | 0.96 | NPC1 (0.79) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13661875 | 0.96 | NPC1 (0.79) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17620451 | 0.96 | NPC1 (0.79) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL23642679 | 0.96 | NPC1 (0.79) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13661877 | 0.96 | NPC1 (0.79) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL126684 | 0.96 | NPC1 (0.79) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL179687 | 0.96 | NPC1 (0.79) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL127568 | 0.96 | NPC1 (0.79) | NPC1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150297738-A1 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2015-10-22 | — | — | US | disclosed |
| US-20150297738-A1 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2015-10-22 | — | — | US | disclosed |
| US-20140088298-A9 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2014-03-27 | — | — | US | disclosed |
| US-20140088298-A9 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2014-03-27 | — | — | US | disclosed |
| US-20140073779-A9 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2014-03-13 | — | — | US | disclosed |
| US-20140073779-A9 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2014-03-13 | — | — | US | disclosed |
| US-20130211060-A1 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2013-08-15 | — | — | US | disclosed |
| US-20130211060-A1 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2013-08-15 | — | — | US | disclosed |
| US-20130184455-A1 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2013-07-18 | — | — | US | disclosed |
| US-20130184455-A1 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2013-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140088298-A9 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION | HACL2, HASPIN, LIPA | NPC1 2629/4885TUBB4A 1604/4885TUBB 1505/4885 |
| US-20130211060-A1 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION | HACL2, HASPIN, LIPA | NPC1 2629/4885TUBB4A 1604/4885TUBB 1505/4885 |
| US-20150297738-A1 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION | HASPIN, HACL2, PCNA | NPC1 1628/4885TUBB4A 1439/4885TUBB 1393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.