Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.79 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.79 |
| ▸ | TUBB | P07437 | 4/20 | 0.79 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.79 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.79 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.79 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.79 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.79 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.79 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.79 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.79 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.79 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.79 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.79 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.79 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.79 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.79 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.79 |
| ▸ | MEN1 | O00255 | 2/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17620451 | 1.00 | NPC1 (0.79) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13661869 | 1.00 | NPC1 (0.79) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13661876 | 1.00 | NPC1 (0.79) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13661877 | 1.00 | NPC1 (0.79) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL126684 | 1.00 | NPC1 (0.79) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL23642679 | 1.00 | NPC1 (0.79) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13661875 | 1.00 | NPC1 (0.79) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13147062 | 0.98 | NPC1 (0.80) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL22787419 | 0.98 | NPC1 (0.80) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL21014339 | 0.97 | NPC1 (0.74) | NPC1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170172975-A1 | NANOPARTICLE FORMULATIONS AND USES THEREOF | ABRAXIS BIOSCIENCE, LLC | 2017-06-22 | — | — | US | disclosed |
| US-20140302157-A1 | NANOPARTICLE FORMULATIONS AND USES THEROF | ABRAXIS BIOSCIENCE, LLC (US) | 2014-10-09 | — | — | US | disclosed |
| US-20140080901-A1 | NANOPARTICLE FORMULATIONS AND USES THEREOF | ABRAXIS BIOSCIENCE, LLC (US) | 2014-03-20 | — | — | US | disclosed |
| US-20130195983-A1 | NANOPARTICLE FORMULATIONS AND USES THEREOF | ABRAXIS BIOSCIENCE, LLC | 2013-08-01 | — | — | US | disclosed |
| US-20090263483-A1 | NANOPARTICLE FORMULATIONS AND USES THEREOF | ABRAXIS BIOSCIENCE, LLC | 2009-10-22 | — | — | US | disclosed |
| US-20090263483-A1 | NANOPARTICLE FORMULATIONS AND USES THEREOF | ABRAXIS BIOSCIENCE, LLC | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130195983-A1 | NANOPARTICLE FORMULATIONS AND USES THEREOF | ABCB1, SLC47A1, ABCC1 | NPC1 6/4885TUBB4A 612/4885TUBB 548/4885 |
| US-20090263483-A1 | NANOPARTICLE FORMULATIONS AND USES THEREOF | ABCB1, SLC47A1, ABCC1 | NPC1 6/4885TUBB4A 612/4885TUBB 548/4885 |
| US-20140302157-A1 | NANOPARTICLE FORMULATIONS AND USES THEROF | TSG101, HDGF, TP53 | NPC1 77/4885TUBB4A 901/4885TUBB 826/4885 |
| US-20170172975-A1 | NANOPARTICLE FORMULATIONS AND USES THEREOF | ABCB1, SLC47A1, ABCC1 | NPC1 6/4885TUBB4A 612/4885TUBB 548/4885 |
| US-20140080901-A1 | NANOPARTICLE FORMULATIONS AND USES THEREOF | ABCB1, SLC47A1, ABCC1 | NPC1 6/4885TUBB4A 612/4885TUBB 548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.