SCHEMBL15134182

SCHEMBL15134182

CO[Si](C)(CCCOCC(O)CN(C)CC(O)C(O)C(O)C(O)CO)OC

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.36
SPHK1 Q9NYA1 1/20 0.31
CASR P41180 1/20 0.31
TOP1 P11387 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20907744 0.89 USP2 (0.35) USP2SPHK1
SCHEMBL16273077 0.85 USP2 (0.33) USP2
SCHEMBL1244943 0.84 USP2 (0.35) USP2SPHK1
SCHEMBL20905013 0.84 USP2 (0.32) USP2
SCHEMBL12760982 0.83 USP2 (0.50) USP2SPHK1CASRTOP1HTT
SCHEMBL21273249 0.80 USP2 (0.59) USP2SPHK1CASRHTT
SCHEMBL31314692 0.80 USP2 (0.59) USP2SPHK1CASRHTT
SCHEMBL15381387 0.80 USP2 (0.41) USP2SPHK1CASRTOP1HTT
SCHEMBL27965037 0.79 USP2 (0.32) USP2
SCHEMBL23615822 0.78 USP2 (0.39) USP2SPHK1CASRTOP1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160185916-A1 METHODS OF MAKING SACCHARIDE SILOXANE COPOLYMERS DOW CORNING (US) 2016-06-30 US disclosed
US-20160185916-A1 METHODS OF MAKING SACCHARIDE SILOXANE COPOLYMERS DOW CORNING (US) 2016-06-30 US disclosed
US-9315631-B2 Methods of making saccharide siloxane copolymers DOW CORNING CORPORATION (US) 2016-04-19 US disclosed
US-9315631-B2 Methods of making saccharide siloxane copolymers DOW CORNING CORPORATION (US) 2016-04-19 US disclosed
US-20140357884-A1 Methods of Making Saccharide Siloxane Copolymers DOW CORNING CORPORATION (US) 2014-12-04 US disclosed
US-20140357884-A1 Methods of Making Saccharide Siloxane Copolymers DOW CORNING CORPORATION (US) 2014-12-04 US disclosed
WO-2013109523-A1 METHODS OF MAKING SACCHARIDE SILOXANE COPOLYMERS DOW CORNING CORPORATION (US) 2013-07-25 WO disclosed