Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | TOP1 | P11387 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CASR | P41180 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12760982 | 0.86 | USP2 (0.50) | USP2TOP1SPHK1PLA2G2CHTT | |
| SCHEMBL31314692 | 0.83 | USP2 (0.59) | USP2SPHK1PLA2G2CHTTCYP3A4 | |
| SCHEMBL21273249 | 0.83 | USP2 (0.59) | USP2SPHK1PLA2G2CHTTCYP3A4 | |
| SCHEMBL15381387 | 0.83 | USP2 (0.41) | USP2TOP1SPHK1HTTLMNA | |
| SCHEMBL19546179 | 0.83 | USP2 (0.38) | USP2TOP1SPHK1HTT | |
| SCHEMBL23615811 | 0.81 | LMNA (0.39) | USP2SPHK1PLA2G2CLMNACYP3A4 | |
| SCHEMBL15134188 | 0.80 | USP2 (0.38) | USP2TOP1SPHK1HTT | |
| SCHEMBL17880770 | 0.78 | USP2 (0.36) | USP2TOP1SPHK1HTTCASR | |
| SCHEMBL15134182 | 0.78 | USP2 (0.36) | USP2TOP1SPHK1HTTCASR | |
| SCHEMBL23615808 | 0.78 | LMNA (0.34) | USP2SPHK1PLA2G2CLMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3448974-B1 | DETERGENT COMPOSITION COMPRISING A CARBINOL FUNCTIONAL TRISILOXANE | DOW SILICONES CORP (US) | 2021-07-07 | — | — | EP | disclosed |