SCHEMBL15144192

SCHEMBL15144192

c1cc(-n2c3ccccc3c3ccccc32)cc(-n2c3ccccc3c3c2c2ccccc2n3-c2ccc3ccc(-n4c5ccccc5c5c4c4ccccc4n5-c4cccc(-n5c6ccccc6c6ccccc65)c4)cc3c2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.50
ATM Q13315 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
F2 P00734 1/20 0.36
F10 P00742 1/20 0.36
PRSS1 P07477 1/20 0.36
PTPN1 P18031 2/20 0.33
ALDH1A1 P00352 2/20 0.33
RAB9A P51151 2/20 0.33
PMM2 O15305 1/20 0.33
MPI P34949 1/20 0.33
PHOSPHO1 Q8TCT1 1/20 0.33
NPC1 O15118 1/20 0.33
POLB P06746 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HPGD P15428 1/20 0.32
FOLH1 Q04609 1/20 0.32
MAPK8 P45983 1/20 0.32
MAPK9 P45984 1/20 0.32
DUSP3 P51452 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19769460 0.90 KDM4E (0.47) KDM4EATML3MBTL1F2F10
SCHEMBL15128411 0.89 L3MBTL1 (0.61) KDM4EATML3MBTL1PTPN1ALDH1A1
SCHEMBL26809883 0.89 KDM4E (0.44) KDM4EATML3MBTL1F2F10
SCHEMBL17689873 0.86 L3MBTL1 (0.69) KDM4EATML3MBTL1PTPN1ALDH1A1
SCHEMBL15164818 0.85 KDM4E (0.44) KDM4EATML3MBTL1F2F10
SCHEMBL19863517 0.84 KDM4E (0.59) KDM4EATML3MBTL1PTPN1ALDH1A1
SCHEMBL19769472 0.83 KDM4E (0.50) KDM4EATML3MBTL1F2F10
SCHEMBL10027551 0.83 KDM4E (0.44) KDM4EATML3MBTL1F2F10
SCHEMBL274318 0.82 KDM4E (0.56) KDM4EATML3MBTL1F2F10
SCHEMBL15144191 0.82 L3MBTL1 (0.61) KDM4EATML3MBTL1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2629345-B1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL & SUMIKIN CHEM CO (JP) 2017-12-06 EP disclosed
US-9312496-B2 Organic electroluminescent element NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2016-04-12 US disclosed
US-9312496-B2 Organic electroluminescent element NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2016-04-12 US disclosed
EP-2629345-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Nippon Steel & Sumikin Chemical Co., Ltd. (JP) 2013-08-21 EP disclosed
US-20130193429-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2013-08-01 US disclosed
US-20130193429-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2013-08-01 US disclosed