⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12377629 | 0.70 | — | — | |
| SCHEMBL9475016 | 0.67 | — | — | |
| SCHEMBL377192 | 0.67 | — | — | |
| SCHEMBL17891670 | 0.64 | — | — | |
| SCHEMBL15843590 | 0.64 | — | — | |
| SCHEMBL7714659 | 0.64 | — | — | |
| SCHEMBL690006 | 0.64 | — | — | |
| SCHEMBL248844 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL9475020 | 0.64 | — | — | |
| SCHEMBL6739107 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024094170-A1 | INHIBITOR OF UBIQUITIN-SPECIFIC PROTEASE 1 AND USE THEREOF | 深圳晶泰科技有限公司 | 2024-05-10 | — | — | WO | claimed |
| CN-113457746-B | Catalyst and preparation method and application thereof | 南方科技大学 | 2023-08-22 | — | — | CN | claimed |
| CN-114181250-A | Alkenyl phosphine compound and preparation method thereof | 中国石油化工股份有限公司 | 2022-03-15 | — | — | CN | claimed |
| CN-113457746-A | Catalyst and preparation method and application thereof | 南方科技大学 | 2021-10-01 | — | — | CN | claimed |
| EP-3290420-B1 | PYRIMIDINE PYRROLE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND USES THEREOF | UNIV XIAMEN (CN) | 2020-12-09 | — | — | EP | claimed |
| US-20200207779-A2 | THIENOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | Hongyun Biotech Co., Ltd. (CN) | 2020-07-02 | — | — | US | claimed |
| US-20190211030-A1 | THIENOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | Hongyun Biotech Co., Ltd. (CN) | 2019-07-11 | — | — | US | claimed |
| EP-3498716-A1 | THIENOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND APPLICATIONS | Hongyun Biotech Co., Ltd. (CN) | 2019-06-19 | — | — | EP | claimed |
| US-20180312508-A1 | PYRIMIDOPYRROLE COMPOUNDS, METHOD FOR PREPARING THE SAME, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME AND USES THEREOF | XIAMEN UNIVERSITY (CN) | 2018-11-01 | — | — | US | claimed |
| EP-3290420-A1 | PYRIMIDINE PYRROLE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND USES THEREOF | Xiamen University (CN) | 2018-03-07 | — | — | EP | claimed |
| EP-1019411-A1 | PROCESS FOR SYNTHESIZING CARBAPENEM SIDE CHAIN INTERMEDIATES | Merck & Co., Inc. (US) | 2000-07-19 | — | — | EP | claimed |
| US-6063931-A | REACTING 4-HYDROXYPROLINE N-PROTECTED WITH AN OXYCARBONYL OR PHOSPHORYL GROUP WITH DIPHENYLPHOSPHINIC CHLORIDE, METHANESULFONYLATION OF HYDROXY GROUP AND COMBINING PRODUCT IN WATER WITH A METAL SULFIDE TO FORM CYCLIZED FINAL PRODUCT | MERCK & CO., INC. (US) | 2000-05-16 | — | — | US | claimed |
| US-6060607-A | CARBAPENEM INTERMEDIATE REACTED WITH DIPHENYLPHOSPHINIC CHLORIDE TO ACTIVATE THE CARBOXYLIC ACID GROUP, AND THEN REACTED WITH METHANESULFONYL CHLORIDE TO PRODUCE PRODUCT WHICH IS REACTED WITH A GROUP II METAL SULFIDE SOURCE | MERCK & CO., INC. (US) | 2000-05-09 | — | — | US | claimed |
| EP-0708109-B1 | Process for the preparation of dicarbonic acids containing phosphorus | CLARIANT GMBH (DE) | 2000-03-01 | — | — | EP | claimed |
| WO-1999002531-A1 | PROCESS FOR SYNTHESIZING CARBAPENEM SIDE CHAIN INTERMEDIATES | MERCK & CO., INC. (US) | 1999-01-21 | — | — | WO | claimed |
| US-5847184-A | Process for preparing phosphorus-containing dicarboxylic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | claimed |
| US-5693842-A | Process for preparing phosphorus-containing dicarboxylic acids alkyl esters thereof | HOECHST AG (DE) | 1997-12-02 | — | — | US | claimed |
| EP-0337637-B1 | 2-(Heterocyclylthio)carbapenem derivatives their preparation and their use as antibiotics | SANKYO CO (JP) | 1994-11-30 | — | — | EP | claimed |
| EP-0597821-A1 | 2-(Heterocyclylthio)carbapenem derivatives their preparation and their use as antibiotics | Sankyo Company Limited (JP) | 1994-05-18 | — | — | EP | claimed |
| EP-0300988-A2 | Tissue factor inhibitor | WASHINGTON UNIVERSITY (US) | 1989-01-25 | — | — | EP | claimed |