Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.70 |
| ▸ | NPC1 | O15118 | 7/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.70 |
| ▸ | RAB9A | P51151 | 6/20 | 0.70 |
| ▸ | HTT | P42858 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SCD | O00767 | 3/20 | 0.47 |
| ▸ | SCD5 | Q86SK9 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15190389 | 0.91 | ALDH1A1 (0.58) | ALDH1A1NPC1SMN1; SMN2RAB9AHTT | |
| SCHEMBL15190211 | 0.90 | ALDH1A1 (0.57) | ALDH1A1NPC1SMN1; SMN2RAB9AHTT | |
| SCHEMBL15190289 | 0.88 | ALDH1A1 (0.68) | ALDH1A1NPC1SMN1; SMN2RAB9AHTT | |
| SCHEMBL15190413 | 0.88 | NPC1 (0.73) | ALDH1A1NPC1SMN1; SMN2RAB9AHTT | |
| SCHEMBL15190040 | 0.86 | SMN1; SMN2 (0.59) | ALDH1A1NPC1SMN1; SMN2RAB9AHTT | |
| SCHEMBL15190165 | 0.85 | ALDH1A1 (0.52) | ALDH1A1NPC1SMN1; SMN2RAB9AHTT | |
| SCHEMBL15190254 | 0.84 | ALDH1A1 (0.49) | ALDH1A1NPC1SMN1; SMN2RAB9AHTT | |
| SCHEMBL15190108 | 0.83 | ALDH1A1 (0.49) | ALDH1A1NPC1SMN1; SMN2RAB9AHTT | |
| SCHEMBL1475653 | 0.83 | NPC1 (1.00) | ALDH1A1NPC1SMN1; SMN2RAB9AHTT | |
| SCHEMBL15190362 | 0.82 | NPC1 (0.48) | ALDH1A1NPC1SMN1; SMN2RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971600-B1 | ISOXAZOLE DERIVATIVES AND USE THEREOF | SK BIOPHARMACEUTICALS CO LTD (KR) | 2013-08-21 | — | — | EP | claimed |