Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 16/20 | 0.62 |
| ▸ | ROCK2 | O75116 | 15/20 | 0.62 |
| ▸ | PRKACA | P17612 | 15/20 | 0.62 |
| ▸ | CDK2 | P24941 | 14/20 | 0.62 |
| ▸ | HIPK2 | Q9H2X6 | 14/20 | 0.62 |
| ▸ | GSK3B | P49841 | 13/20 | 0.62 |
| ▸ | PIM1 | P11309 | 13/20 | 0.62 |
| ▸ | IRAK4 | Q9NWZ3 | 8/20 | 0.62 |
| ▸ | CDK7 | P50613 | 7/20 | 0.62 |
| ▸ | CDK9 | P50750 | 7/20 | 0.62 |
| ▸ | DYRK1A | Q13627 | 9/20 | 0.60 |
| ▸ | MELK | Q14680 | 7/20 | 0.60 |
| ▸ | STK17A | Q9UEE5 | 7/20 | 0.60 |
| ▸ | CLK2 | P49760 | 7/20 | 0.60 |
| ▸ | CDK5 | Q00535 | 7/20 | 0.60 |
| ▸ | DAPK3 | O43293 | 6/20 | 0.60 |
| ▸ | PRKX | P51817 | 6/20 | 0.60 |
| ▸ | PKN2 | Q16513 | 6/20 | 0.60 |
| ▸ | CSNK1A1 | P48729 | 6/20 | 0.60 |
| ▸ | PRKD3 | O94806 | 5/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1042608 | 0.84 | BRD4 (0.70) | CDC7ROCK2PRKACACDK2HIPK2 | |
| SCHEMBL1045853 | 0.82 | ROCK2 (0.71) | CDC7ROCK2PRKACACDK2HIPK2 | |
| SCHEMBL1045597 | 0.82 | CDC7 (0.63) | CDC7ROCK2PRKACACDK2HIPK2 | |
| SCHEMBL27914512 | 0.80 | BRD4 (0.57) | CDC7ROCK2PRKACACDK2HIPK2 | |
| SCHEMBL1043490 | 0.79 | CDC7 (0.82) | CDC7ROCK2PRKACACDK2HIPK2 | |
| SCHEMBL1045994 | 0.78 | ROCK2 (0.62) | CDC7ROCK2PRKACACDK2HIPK2 | |
| SCHEMBL1044690 | 0.78 | EGFR (0.59) | CDC7GSK3BEGFRALKLRRK2 | |
| SCHEMBL1042897 | 0.78 | CDC7 (0.61) | CDC7ROCK2PRKACACDK2HIPK2 | |
| SCHEMBL1043581 | 0.78 | CDK2 (0.73) | CDC7ROCK2PRKACACDK2HIPK2 | |
| SCHEMBL1045905 | 0.78 | CDC7 (0.61) | CDC7ROCK2PRKACACDK2HIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2454257-B1 | PYRROLOPYRIDINE INHIBITORS OF KINASES | ABBVIE INC (US) | 2013-08-21 | — | — | EP | claimed |