Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.71 |
| ▸ | MAPT | P10636 | 4/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.66 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4810433 | 0.84 | KMT2A (0.68) | KMT2AMAPTL3MBTL1HPGDALDH1A1 | |
| SCHEMBL27364435 | 0.83 | KMT2A (0.67) | KMT2AMAPTL3MBTL1HPGDALDH1A1 | |
| SCHEMBL27555836 | 0.83 | KMT2A (0.67) | KMT2AMAPTL3MBTL1HPGDALDH1A1 | |
| SCHEMBL5710377 | 0.83 | KMT2A (0.67) | KMT2AMAPTL3MBTL1HPGDALDH1A1 | |
| Iodide SCHEMBL30758523 | 0.82 | KMT2A (0.66) | KMT2AMAPTL3MBTL1HPGDALDH1A1 | |
| SCHEMBL15200218 | 0.82 | KMT2A (0.61) | KMT2AMAPTL3MBTL1HPGDALDH1A1 | |
| SCHEMBL12768195 | 0.82 | KMT2A (0.66) | KMT2AMAPTL3MBTL1HPGDALDH1A1 | |
| SCHEMBL8157515 | 0.81 | KMT2A (0.49) | KMT2AMAPTL3MBTL1HPGDALDH1A1 | |
| SCHEMBL15009623 | 0.80 | KMT2A (0.63) | KMT2AMAPTL3MBTL1HPGDALDH1A1 | |
| SCHEMBL10530079 | 0.80 | KMT2A (1.00) | KMT2AMAPTL3MBTL1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10548911-B2 | Small molecule anti-scarring agents | UNIVERSITY OF ROCHESTER (US) | 2020-02-04 | — | — | US | disclosed |
| US-20170216332-A1 | SMALL MOLECULE ANTI-SCARRING AGENTS | UNIVERSITY OF ROCHESTER (US) | 2017-08-03 | — | — | US | disclosed |
| US-8962244-B2 | Compounds for modulating RNA binding proteins and uses therefor | UNIVERSITY OF MASSACHUSETTS (US) | 2015-02-24 | — | — | US | disclosed |
| US-20130217685-A1 | COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR | UNIVERSITY OF MASSACHUSETTS (US) | 2013-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130217685-A1 | COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR | TIA1, ZFP3, RBM3 | KMT2A 3013/4885MAPT 4038/4885L3MBTL1 63/4885 |
| US-20170216332-A1 | SMALL MOLECULE ANTI-SCARRING AGENTS | COLGALT1, MMP1, FIBP | KMT2A 3498/4885MAPT 4802/4885L3MBTL1 867/4885 |
| US-10548911-B2 | Small molecule anti-scarring agents | COLGALT1, MMP1, FIBP | KMT2A 3498/4885MAPT 4802/4885L3MBTL1 867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.