Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15200470 | 1.00 | ATM (0.61) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL15200457 | 1.00 | ATM (0.61) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL30776760 | 0.92 | ATM (0.64) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL30776759 | 0.92 | ATM (0.64) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL15200473 | 0.89 | ATM (0.59) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL15200510 | 0.88 | ATM (0.47) | ATMTDP1L3MBTL1PBRM1MEN1 | |
| SCHEMBL15200477 | 0.88 | ATM (0.47) | ATMTDP1L3MBTL1PBRM1MEN1 | |
| SCHEMBL15200505 | 0.86 | TDP1 (0.53) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL15200411 | 0.86 | TDP1 (0.53) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL19421027 | 0.86 | ATM (0.52) | ATMTDP1L3MBTL1ALDH1A1PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130214267-A1 | SPIRO[CYCLOPENTA[def]TRIPHENYLENE-4,9'-FLUORENE] COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE HAVING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2013-08-22 | — | — | US | disclosed |