Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15200505 | 1.00 | TDP1 (0.53) | TDP1ATML3MBTL1KMOPBRM1 | |
| SCHEMBL15200477 | 0.91 | ATM (0.47) | TDP1ATML3MBTL1KMOPBRM1 | |
| SCHEMBL15200510 | 0.91 | ATM (0.47) | TDP1ATML3MBTL1KMOPBRM1 | |
| SCHEMBL15200499 | 0.91 | TDP1 (0.46) | TDP1ATML3MBTL1KMOPBRM1 | |
| SCHEMBL15200500 | 0.88 | KMO (0.46) | TDP1ATML3MBTL1KMOPBRM1 | |
| SCHEMBL15200457 | 0.86 | ATM (0.61) | TDP1ATML3MBTL1PBRM1ALDH1A1 | |
| SCHEMBL15200470 | 0.86 | ATM (0.61) | TDP1ATML3MBTL1PBRM1ALDH1A1 | |
| SCHEMBL15200461 | 0.86 | ATM (0.61) | TDP1ATML3MBTL1PBRM1ALDH1A1 | |
| SCHEMBL6128488 | 0.84 | PDK2 (0.44) | TDP1ATML3MBTL1KMOPBRM1 | |
| SCHEMBL8438374 | 0.82 | ATM (0.77) | TDP1ATML3MBTL1KMOPBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130214267-A1 | SPIRO[CYCLOPENTA[def]TRIPHENYLENE-4,9'-FLUORENE] COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE HAVING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2013-08-22 | — | — | US | disclosed |