Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 7/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 7/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | CASP7 | P55210 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29699646 | 0.75 | MEN1 (0.41) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL3486438 | 0.75 | MEN1 (0.41) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL4846708 | 0.75 | MEN1 (0.48) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL14252755 | 0.75 | MEN1 (0.50) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL27896979 | 0.73 | MEN1 (0.48) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL1421455 | 0.73 | MAPT (0.58) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL1421620 | 0.73 | MAPT (0.58) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL12690913 | 0.72 | CSNK2A2 (0.49) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL2997729 | 0.72 | CSNK2A2 (0.47) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL1421976 | 0.72 | TUBB4A (0.55) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2631232-B1 | Halogen derivatives of benzo[b]furans useful as anti-neoplastic or anti-proliferative drugs | CT BADAN MOLEKULAR I MAKRO (PL) | 2015-09-16 | — | — | EP | disclosed |
| EP-2631232-A1 | Halogen derivatives of benzo[b]furans useful as anti-neoplastic or anti-proliferative drugs | Centrum Badan Molekularnych I Makromolekularnych Pan (PL) | 2013-08-28 | — | — | EP | disclosed |