Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.76 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.76 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.76 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.76 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.76 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.76 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.76 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.76 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.76 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.76 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.76 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1521045 | 1.00 | HDAC1 (0.76) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL3715218 | 1.00 | HDAC1 (0.76) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL1521099 | 0.91 | HDAC1 (0.72) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL1521100 | 0.91 | HDAC1 (0.72) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL1520926 | 0.89 | HDAC1 (0.69) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL1520929 | 0.89 | HDAC1 (0.69) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL13456909 | 0.87 | HDAC1 (0.71) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| Trichostatin SCHEMBL446806 | 0.86 | HDAC1 (1.00) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| Trichostatin SCHEMBL446807 | 0.86 | HDAC1 (1.00) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| Trichostatin SCHEMBL675951 | 0.86 | HDAC1 (1.00) | HDAC1HDAC3HDAC4HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160015693-A1 | METHODS AND COMPOUNDS FOR PREVENTING AND TREATING A TUMOUR | AGENCY SCIENCE TECH & RES (SG) | 2016-01-21 | — | — | US | disclosed |
| US-8969313-B2 | Methods and compounds for preventing and treating a tumour | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2015-03-03 | — | — | US | disclosed |
| US-20110053882-A1 | METHODS AND COMPOUNDS FOR PREVENTING AND TREATING A TUMOUR | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2011-03-03 | — | — | US | disclosed |
| EP-2217240-A1 | METHODS AND COMPOUNDS FOR PREVENTING AND TREATING A TUMOUR | Agency for Science, Technology And Research (SG) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009058102-A1 | METHODS AND COMPOUNDS FOR PREVENTING AND TREATING A TUMOUR | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2009-05-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053882-A1 | METHODS AND COMPOUNDS FOR PREVENTING AND TREATING A TUMOUR | HDAC1, CCAR2, HDAC11 | HDAC1 1/4885HDAC3 4/4885HDAC4 24/4885 |
| US-20160015693-A1 | METHODS AND COMPOUNDS FOR PREVENTING AND TREATING A TUMOUR | HDAC1, HDAC11, CCAR2 | HDAC1 1/4885HDAC3 4/4885HDAC4 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.