Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 16/20 | 0.72 |
| ▸ | FFAR4 | Q5NUL3 | 8/20 | 0.72 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.67 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.60 |
| ▸ | LTK | P29376 | 1/20 | 0.60 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.60 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.60 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.55 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15211590 | 0.86 | NR4A2 (0.59) | FFAR1FFAR4NR4A2S1PR1LTK | |
| SCHEMBL966182 | 0.83 | KMT2A (0.67) | FFAR1FFAR4NR4A2S1PR1LTK | |
| SCHEMBL28927554 | 0.82 | FFAR1 (0.69) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL30172602 | 0.82 | FFAR1 (0.69) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL11705511 | 0.81 | NR4A2 (0.58) | FFAR1FFAR4NR4A2S1PR1LTK | |
| SCHEMBL11656658 | 0.81 | FFAR1 (0.58) | FFAR1FFAR4NR4A2 | |
| SCHEMBL11702978 | 0.80 | S1PR1 (0.63) | FFAR1FFAR4S1PR1S1PR5MEN1 | |
| SCHEMBL5514493 | 0.80 | KMT2A (0.67) | FFAR1FFAR4NR4A2S1PR1LTK | |
| SCHEMBL1746557 | 0.79 | FFAR1 (0.67) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL5510087 | 0.78 | NR4A2 (0.61) | FFAR1NR4A2S1PR1LTKTAOK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838891-B1 | AROMATIC RING COMPOUND AS GHRELIN O-ACYLTRANSFERASE INHIBITOR | TAKEDA PHARMACEUTICALS CO (JP) | 2017-08-02 | — | — | EP | disclosed |
| US-9238639-B2 | Aromatic ring compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-01-19 | — | — | US | disclosed |
| EP-2838891-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-02-25 | — | — | EP | disclosed |
| WO-2013125732-A1 | AROMATIC RING COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-08-29 | — | — | WO | disclosed |