Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 12/20 | 0.43 |
| ▸ | PPARA | Q07869 | 11/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.34 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15211352 | 0.90 | PPARD (0.45) | PPARDPPARAPPARGMBOAT4ITGB3 | |
| SCHEMBL15211263 | 0.84 | PPARD (0.40) | PPARDPPARAPPARG | |
| SCHEMBL15211556 | 0.83 | PPARD (0.63) | PPARDPPARAPPARGMBOAT4ITGB3 | |
| SCHEMBL15210895 | 0.82 | PPARD (0.43) | PPARDPPARAPPARGITGB3ITGB1 | |
| SCHEMBL15211367 | 0.82 | PPARD (0.40) | PPARDPPARAPPARGITGB3ITGB1 | |
| SCHEMBL17444900 | 0.81 | PPARD (0.50) | PPARDPPARAPPARGMBOAT4MAPT | |
| SCHEMBL17431353 | 0.80 | PPARA (0.42) | PPARDPPARAPPARGMBOAT4ITGB3 | |
| SCHEMBL15211282 | 0.79 | NR4A2 (0.49) | PPARDPPARAMAPTALDH1A1 | |
| SCHEMBL15211398 | 0.78 | PPARD (0.46) | PPARDPPARAPPARGMAPTALDH1A1 | |
| SCHEMBL15211405 | 0.78 | PPARD (0.40) | PPARDPPARAPPARGITGB3ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838891-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-02-25 | — | — | EP | disclosed |
| WO-2013125732-A1 | AROMATIC RING COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-08-29 | — | — | WO | disclosed |