Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 15/20 | 0.43 |
| ▸ | PPARA | Q07869 | 13/20 | 0.43 |
| ▸ | PPARG | P37231 | 5/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.35 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | F9 | P00740 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15211405 | 0.87 | PPARD (0.40) | PPARDPPARAPPARGITGB3ITGB1 | |
| SCHEMBL15211442 | 0.85 | ALDH1A1 (0.39) | PPARDPPARAPPARGITGB3ITGB1 | |
| SCHEMBL15211352 | 0.85 | PPARD (0.45) | PPARDPPARAPPARGITGB3ITGB1 | |
| SCHEMBL15211308 | 0.84 | PPARD (0.37) | PPARDPPARAPPARGITGB3ITGB1 | |
| SCHEMBL15210894 | 0.83 | PPARD (0.63) | PPARDPPARAPPARGITGB3ITGB1 | |
| SCHEMBL15211710 | 0.83 | PPARD (0.47) | PPARDPPARAPPARGITGB3ITGB1 | |
| SCHEMBL17444882 | 0.82 | PPARD (0.52) | PPARDPPARAPPARGITGB3ITGB1 | |
| SCHEMBL15211464 | 0.82 | PPARD (0.43) | PPARDPPARAPPARGITGB3ITGB1 | |
| SCHEMBL15211449 | 0.80 | PPARD (0.42) | PPARDPPARAPPARGITGB3ITGB1 | |
| SCHEMBL17431488 | 0.80 | PPARA (0.44) | PPARDPPARAPPARGITGB3ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838891-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-02-25 | — | — | EP | disclosed |
| WO-2013125732-A1 | AROMATIC RING COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-08-29 | — | — | WO | disclosed |