Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 14/20 | 0.73 |
| ▸ | IDO1 | P14902 | 15/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14686234 | 0.98 | AGXT (0.71) | AGXTIDO1CYP3A4AOC3 | |
| SCHEMBL1521029 | 0.85 | AGXT (1.00) | AGXTIDO1CYP3A4 | |
| SCHEMBL1521252 | 0.82 | AGXT (0.73) | AGXTIDO1CYP3A4 | |
| SCHEMBL1521114 | 0.80 | IDO1 (0.64) | AGXTIDO1CYP3A4 | |
| SCHEMBL3723971 | 0.79 | TAAR1 (0.69) | TAAR1AOC3 | |
| SCHEMBL1520718 | 0.79 | AGXT (0.69) | AGXTIDO1 | |
| SCHEMBL30079884 | 0.79 | IDO1 (1.00) | AGXTIDO1CYP3A4TAAR1 | |
| SCHEMBL403680 | 0.79 | IDO1 (1.00) | AGXTIDO1CYP3A4TAAR1 | |
| SCHEMBL1521290 | 0.79 | AGXT (0.73) | AGXTIDO1CYP3A4 | |
| Hydrochloric Acid SCHEMBL184282 | 0.78 | TAAR1 (0.67) | TAAR1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2227233-B1 | IDO INHIBITORS | NEWLINK GENETICS (US) | 2013-02-13 | — | — | EP | claimed |
| US-20110053941-A1 | IDO Inhibitors | NEWLINK GENETICS (US) | 2011-03-03 | — | — | US | claimed |
| EP-2227233-A2 | IDO INHIBITORS | Newlink Genetics (US) | 2010-09-15 | — | — | EP | claimed |
| WO-2009073620-A2 | IDO INHIBITORS | NEWLINK GENETICS (US) | 2009-06-11 | — | — | WO | claimed |
| US-20130289083-A1 | IDO Inhibitors | NEWLINK GENETICS CORPORATION | 2013-10-31 | — | — | US | disclosed |
| EP-2227233-B1 | IDO INHIBITORS | NEWLINK GENETICS (US) | 2013-02-13 | — | — | EP | disclosed |
| US-20110053941-A1 | IDO Inhibitors | NEWLINK GENETICS (US) | 2011-03-03 | — | — | US | disclosed |
| US-20110053941-A1 | IDO Inhibitors | NEWLINK GENETICS (US) | 2011-03-03 | — | — | US | disclosed |
| US-20110053941-A1 | IDO Inhibitors | NEWLINK GENETICS (US) | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053941-A1 | IDO Inhibitors | IDO1, IDO2, INMT | AGXT 365/4885IDO1 1/4885CYP3A4 413/4885 |
| US-20130289083-A1 | IDO Inhibitors | IDO1, IDO2, INMT | AGXT 285/4885IDO1 1/4885CYP3A4 499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.