Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 18/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.74 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL643754 | 0.85 | ALPL (1.00) | ALPLLMNASMN1; SMN2KMT2A | |
| SCHEMBL29357421 | 0.85 | ALPL (1.00) | ALPLLMNASMN1; SMN2KMT2A | |
| SCHEMBL30695699 | 0.85 | ALPL (1.00) | ALPLLMNASMN1; SMN2KMT2A | |
| SCHEMBL15211743 | 0.83 | ALPL (1.00) | ALPLLMNASMN1; SMN2RAB9AKMT2A | |
| SCHEMBL15220358 | 0.79 | ALPL (0.76) | ALPLLMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL21226601 | 0.76 | ALPL (0.83) | ALPLLMNASMN1; SMN2 | |
| SCHEMBL15211728 | 0.76 | ALPL (1.00) | ALPLLMNASMN1; SMN2SLC22A12 | |
| SCHEMBL22501445 | 0.75 | ALPL (0.70) | ALPLLMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL15211692 | 0.74 | ALPL (1.00) | ALPLLMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL645105 | 0.74 | ALPL (0.69) | ALPLLMNASMN1; SMN2RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2817292-A1 | SULFONAMIDE COMPOUNDS AND USES AS TNAP INHIBITORS | Sanford-Burnham Medical Research Institute (US) | 2014-12-31 | — | — | EP | disclosed |
| WO-2013126608-A1 | SULFONAMIDE COMPOUNDS AND USES AS TNAP INHIBITORS | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2013-08-29 | — | — | WO | disclosed |