Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 3/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PEPD | P12955 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16338335 | 1.00 | ANPEP (0.51) | ANPEPMMP2CYP3A4ALDH1A1MAPK1 | |
| SCHEMBL15211861 | 0.99 | ANPEP (0.50) | ANPEPMMP2CYP3A4ALDH1A1MAPK1 | |
| SCHEMBL15221376 | 0.99 | ANPEP (0.50) | ANPEPMMP2CYP3A4ALDH1A1MAPK1 | |
| SCHEMBL15221392 | 0.99 | ANPEP (0.50) | ANPEPMMP2CYP3A4ALDH1A1MAPK1 | |
| SCHEMBL15211791 | 0.99 | ANPEP (0.50) | ANPEPMMP2CYP3A4ALDH1A1MAPK1 | |
| SCHEMBL15221406 | 0.99 | ANPEP (0.50) | ANPEPMMP2CYP3A4ALDH1A1MAPK1 | |
| SCHEMBL15221356 | 0.86 | MEN1 (0.39) | ANPEPMMP2CYP3A4ALDH1A1MAPK1 | |
| SCHEMBL15212085 | 0.86 | MEN1 (0.39) | ANPEPMMP2CYP3A4ALDH1A1MAPK1 | |
| SCHEMBL15212207 | 0.86 | ALDH1A1 (0.47) | ANPEPMMP2CYP3A4ALDH1A1MAPK1 | |
| SCHEMBL15221379 | 0.86 | ALDH1A1 (0.47) | ANPEPMMP2CYP3A4ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2817291-A1 | ANTIVIRAL COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2014-12-31 | — | — | EP | disclosed |
| WO-2013124335-A1 | ANTIVIRAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2013-08-29 | — | — | WO | disclosed |