Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 20/20 | 0.69 |
| ▸ | FGFR3 | P22607 | 14/20 | 0.69 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15217916 | 0.85 | FGFR1 (0.75) | FGFR1FGFR3FGFR4 | |
| SCHEMBL15217809 | 0.85 | FGFR1 (0.66) | FGFR1FGFR3FGFR4 | |
| Hydrochloric Acid SCHEMBL15211735 | 0.85 | FGFR1 (0.74) | FGFR1FGFR3FGFR4 | |
| SCHEMBL15217887 | 0.84 | FGFR1 (0.70) | FGFR1FGFR3FGFR4 | |
| SCHEMBL15212679 | 0.83 | FGFR1 (0.72) | FGFR1FGFR3 | |
| SCHEMBL15043278 | 0.82 | FGFR1 (1.00) | FGFR1FGFR3FGFR4 | |
| SCHEMBL15217843 | 0.82 | FGFR1 (0.58) | FGFR1FGFR3 | |
| SCHEMBL15217989 | 0.82 | FGFR1 (0.69) | FGFR1FGFR3FGFR4 | |
| Hydrochloric Acid SCHEMBL15212755 | 0.82 | FGFR1 (0.70) | FGFR1FGFR3 | |
| SCHEMBL16419631 | 0.81 | FGFR1 (0.57) | FGFR1FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9475815-B2 | Substituted benzothienyl-pyrrolotriazines and uses thereof | BAYER INTELLETUAL PROPERTY GMBH (DE) | 2016-10-25 | — | — | US | disclosed |
| US-9475815-B2 | Substituted benzothienyl-pyrrolotriazines and uses thereof | BAYER INTELLETUAL PROPERTY GMBH (DE) | 2016-10-25 | — | — | US | disclosed |
| US-9475815-B2 | Substituted benzothienyl-pyrrolotriazines and uses thereof | BAYER INTELLETUAL PROPERTY GMBH (DE) | 2016-10-25 | — | — | US | disclosed |
| EP-2817311-B1 | SUBSTITUTED BENZOTHIENYL-PYRROLOTRIAZINES AND USES THEREOF | BAYER IP GMBH (DE) | 2016-04-06 | — | — | EP | disclosed |
| US-20150031676-A1 | SUBSTITUTED BENZOTHIENYL-PYRROLOTRIAZINES AND USES THEREOF | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-01-29 | — | — | US | disclosed |
| US-20150031676-A1 | SUBSTITUTED BENZOTHIENYL-PYRROLOTRIAZINES AND USES THEREOF | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-01-29 | — | — | US | disclosed |
| US-20150031676-A1 | SUBSTITUTED BENZOTHIENYL-PYRROLOTRIAZINES AND USES THEREOF | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-01-29 | — | — | US | disclosed |
| EP-2817311-A1 | SUBSTITUTED BENZOTHIENYL-PYRROLOTRIAZINES AND USES THEREOF | Bayer Intellectual Property GmbH (DE) | 2014-12-31 | — | — | EP | disclosed |
| WO-2013124316-A1 | SUBSTITUTED BENZOTHIENYL-PYRROLOTRIAZINES AND USES THEREOF | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-08-29 | — | — | WO | disclosed |
| WO-2013124316-A1 | SUBSTITUTED BENZOTHIENYL-PYRROLOTRIAZINES AND USES THEREOF | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150031676-A1 | SUBSTITUTED BENZOTHIENYL-PYRROLOTRIAZINES AND USES THEREOF | STK25, JAK2, PTK2B | FGFR1 186/4885FGFR3 533/4885FGFR4 507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.