Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 15/20 | 0.50 |
| ▸ | PDE4A | P27815 | 10/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6876864 | 0.82 | PDE4B (0.54) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL18920443 | 0.81 | PDE4B (0.53) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL28025842 | 0.81 | PDE4B (0.57) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL20053105 | 0.79 | PDE4B (0.54) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL20448770 | 0.78 | ALDH1A1 (0.46) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL905908 | 0.78 | PDE4B (0.50) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL2913506 | 0.78 | PDE4B (0.50) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL7084190 | 0.78 | PDE4B (0.50) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL28127005 | 0.78 | PDE4B (0.47) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL23365792 | 0.77 | PDE4B (0.61) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2817289-A2 | ASYMMETRIC SYNTHETIC PROCESSES FOR THE PREPARATION OF AMINOSULFONE COMPOUNDS | Celgene Corporation (US) | 2014-12-31 | — | — | EP | disclosed |
| WO-2013126495-A2 | ASYMMETRIC SYNTHETIC PROCESSES FOR THE PREPARATION OF AMINOSULFONE COMPOUNDS | CELGENE CORPORATION (US) | 2013-08-29 | — | — | WO | disclosed |