Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.41 |
| ▸ | PDE4A | P27815 | 4/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL906028 | 0.82 | PTPN1 (0.46) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| Levacetylleucine SCHEMBL21229236 | 0.80 | LMNA (0.45) | ATMPDE4BPDE4APDE4CPDE4D | |
| Levacetylleucine SCHEMBL756572 | 0.80 | LMNA (0.45) | ATMPDE4BPDE4APDE4CPDE4D | |
| Levacetylleucine SCHEMBL302605 | 0.80 | LMNA (0.45) | ATMPDE4BPDE4APDE4CPDE4D | |
| Levacetylleucine SCHEMBL7084218 | 0.80 | LMNA (0.45) | ATMPDE4BPDE4APDE4CPDE4D | |
| Acetylleucine SCHEMBL20474775 | 0.80 | LMNA (0.45) | ATMPDE4BPDE4APDE4CPDE4D | |
| Levacetylleucine SCHEMBL18263873 | 0.79 | LMNA (0.47) | ATMKMT2AMEN1PDE4BPDE4A | |
| Levacetylleucine SCHEMBL7085506 | 0.79 | LMNA (0.47) | ATMKMT2AMEN1PDE4BPDE4A | |
| Levacetylleucine SCHEMBL906113 | 0.79 | LMNA (0.47) | ATMKMT2AMEN1PDE4BPDE4A | |
| Levacetylleucine SCHEMBL702915 | 0.74 | PDE4B (0.43) | ATMPDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2817288-A2 | PROCESSES FOR THE PREPARATION OF (S)-1-(3-ETHOXY-4METHOXYPHENYL)-2-METHANESULFONYLETHYLAMINE | Celgene Corporation (US) | 2014-12-31 | — | — | EP | disclosed |
| WO-2013126360-A2 | PROCESSES FOR THE PREPARATION OF (S)-1-(3-ETHOXY-4METHOXYPHENYL)-2-METHANESULFONYLETHYLAMINE | CELGENE CORPORATION (US) | 2013-08-29 | — | — | WO | disclosed |