Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2082869 | 0.80 | AHR (0.43) | AHRTBXAS1CYP3A4CYP26A1 | |
| SCHEMBL22571992 | 0.76 | AHR (0.57) | AHRTBXAS1CA12CA9ALDH1A1 | |
| SCHEMBL14123361 | 0.76 | AHR (0.48) | AHRTBXAS1ALDH1A1 | |
| Oxalic Acid SCHEMBL22558548 | 0.73 | AHR (0.45) | AHRTBXAS1ALDH1A1 | |
| SCHEMBL10951816 | 0.72 | AHR (0.49) | AHRTBXAS1ALDH1A1 | |
| SCHEMBL1171099 | 0.71 | AHR (0.42) | AHRTBXAS1ALDH1A1 | |
| SCHEMBL28774336 | 0.69 | TBXAS1 (0.42) | AHRTBXAS1TBXA2RALDH1A1 | |
| SCHEMBL12489980 | 0.69 | CA12 (0.41) | AHRTBXAS1CYP3A4CYP19A1CA12 | |
| SCHEMBL4375579 | 0.69 | KMT2A (0.38) | AHRALDH1A1 | |
| SCHEMBL15212788 | 0.69 | TSHR (0.39) | AHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015057847-A1 | CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS | CERULEAN PHARMA INC. (US) | 2015-04-23 | — | — | WO | disclosed |
| EP-2817345-A1 | CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS | Cerulean Pharma Inc. (US) | 2014-12-31 | — | — | EP | disclosed |
| WO-2013126564-A1 | CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS | CERULEAN PHARMA INC. (US) | 2013-08-29 | — | — | WO | disclosed |