SCHEMBL15212995

SCHEMBL15212995

C1=c2nc(-n3c4cc(-c5ccccc5)ccc4c4c5oc6ccccc6c5ccc43)nc(-c3cccc4c3sc3ccccc34)c2=CCC1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 2/20 0.34
PIK3CD O00329 1/20 0.31
PIK3CB P42338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14979550 0.87 PRKDC (0.35) PRKDCPIK3CDPIK3CB
SCHEMBL1755012 0.87 PRKDC (0.30) PRKDC
SCHEMBL1755209 0.85 ALOX5 (0.37) PRKDCPIK3CDPIK3CB
SCHEMBL17117448 0.84 PRKDC (0.35) PRKDCPIK3CDPIK3CB
SCHEMBL1755028 0.83 PRKDC (0.30) PRKDC
SCHEMBL10043349 0.82 PRKDC (0.39) PRKDCPIK3CDPIK3CB
SCHEMBL1755051 0.81 ALOX5 (0.37) PRKDCPIK3CDPIK3CB
SCHEMBL23061473 0.81 PRKDC (0.37) PRKDCPIK3CDPIK3CB
SCHEMBL1755212 0.79
SCHEMBL16283046 0.79 PRKDC (0.39) PRKDCPIK3CDPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013122402-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2013-08-22 WO disclosed