Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.64 |
| ▸ | ALOX5 | P09917 | 10/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.50 |
| ▸ | BID | P55957 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12733119 | 1.00 | TYR (0.64) | TYRALOX5MEN1TP53CYP3A4 | |
| SCHEMBL4969048 | 0.92 | TYR (0.53) | TYRALOX5MEN1TP53CYP3A4 | |
| SCHEMBL11604810 | 0.89 | TYR (0.64) | TYRALOX5MEN1TP53CYP3A4 | |
| SCHEMBL17988280 | 0.85 | TYR (0.46) | TYRALOX5MEN1TP53CYP3A4 | |
| SCHEMBL9513212 | 0.85 | TYR (0.54) | TYRALOX5MEN1TP53CYP3A4 | |
| SCHEMBL31544904 | 0.83 | TYR (0.61) | TYRALOX5MEN1TP53CYP3A4 | |
| SCHEMBL5681264 | 0.83 | TYR (0.56) | TYRALOX5MEN1TP53CYP3A4 | |
| SCHEMBL14347048 | 0.82 | ALOX5 (0.56) | TYRALOX5MEN1TP53CYP3A4 | |
| SCHEMBL11879337 | 0.81 | TYR (0.54) | TYRALOX5MEN1TP53CYP3A4 | |
| SCHEMBL5517885 | 0.81 | TYR (0.59) | TYRALOX5MEN1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8518915-B2 | Use of mitochondrially-addressed compounds for preventing and treating cardiovascular diseases | MITOTECH SA (LU) | 2013-08-27 | — | — | US | disclosed |
| US-8518915-B2 | Use of mitochondrially-addressed compounds for preventing and treating cardiovascular diseases | MITOTECH SA (LU) | 2013-08-27 | — | — | US | disclosed |