Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCRL2 | O00421 | 20/20 | 0.81 |
| ▸ | CCR2 | P41597 | 13/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9999413 | 0.90 | CCRL2 (1.00) | CCRL2CCR2KCNH2 | |
| SCHEMBL12034433 | 0.90 | CCRL2 (1.00) | CCRL2CCR2KCNH2 | |
| SCHEMBL9999412 | 0.90 | CCRL2 (1.00) | CCRL2CCR2KCNH2 | |
| SCHEMBL16838581 | 0.83 | CCRL2 (0.64) | CCRL2CCR2KCNH2 | |
| SCHEMBL12033706 | 0.78 | CCRL2 (0.80) | CCRL2CCR2KCNH2 | |
| SCHEMBL12070897 | 0.78 | CCRL2 (1.00) | CCRL2CCR2KCNH2 | |
| SCHEMBL15214594 | 0.78 | CCRL2 (1.00) | CCRL2CCR2KCNH2 | |
| SCHEMBL9999038 | 0.78 | CCRL2 (1.00) | CCRL2CCR2KCNH2 | |
| SCHEMBL9999037 | 0.78 | CCRL2 (1.00) | CCRL2CCR2KCNH2 | |
| SCHEMBL9999057 | 0.75 | CCRL2 (0.86) | CCRL2CCR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8518969-B2 | Cyclohexyl-azetidinyl antagonists of CCR2 | JANSSEN PHARMACEUTICA NV (BE) | 2013-08-27 | — | — | US | disclosed |