Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12581509 | 0.97 | — | — | |
| SCHEMBL15807044 | 0.97 | — | — | |
| SCHEMBL201444 | 0.91 | HDAC4 (0.32) | HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL16081682 | 0.89 | BACE1 (0.31) | HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL12192210 | 0.89 | BACE1 (0.31) | HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL5830 | 0.89 | BACE1 (0.31) | HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL202259 | 0.85 | BACE1 (0.32) | — | |
| Trifluoromethanesulfonic Acid SCHEMBL3138505 | 0.79 | HDAC4 (0.32) | HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL12893294 | 0.76 | BACE1 (0.33) | — | |
| Formic Acid Methyl Ester SCHEMBL29203565 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8518546-B2 | Photochromic compounds and compositions | TRANSITIONS OPTICAL, INC. (US) | 2013-08-27 | — | — | US | disclosed |