Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SCN1A | P35498 | 2/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | RGS12 | O14924 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16103787 | 1.00 | LMNA (0.50) | LMNATACR1KDM4EADRA2CADRA2A | |
| SCHEMBL4594703 | 0.85 | LMNA (0.50) | LMNAKDM4EADRA2CADRA2AHIF1A | |
| SCHEMBL6558908 | 0.80 | LMNA (0.46) | LMNAKDM4EADRA2CADRA2AHIF1A | |
| SCHEMBL10853706 | 0.80 | LMNA (0.53) | LMNATACR1KDM4EADRA2CADRA2A | |
| SCHEMBL7956563 | 0.80 | LMNA (0.53) | LMNAKDM4EADRA2AALDH1A1SCN1A | |
| SCHEMBL7960344 | 0.80 | LMNA (0.53) | LMNAKDM4EADRA2AALDH1A1SCN1A | |
| SCHEMBL7956561 | 0.80 | LMNA (0.53) | LMNAKDM4EADRA2AALDH1A1SCN1A | |
| SCHEMBL6558628 | 0.79 | LMNA (0.44) | LMNAKDM4EADRA2CADRA2AHIF1A | |
| SCHEMBL6558950 | 0.79 | LMNA (0.44) | LMNAKDM4EADRA2CADRA2AHIF1A | |
| SCHEMBL6559691 | 0.79 | LMNA (0.44) | LMNAKDM4EADRA2CADRA2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8519159-B2 | Tri-substituted 2-benzhydryl-5-benzylamino-tetrahydro-pyran-4-OL and 6-benzhydryl-4-benzylamino-tetrahydro-pyran-3-OL analogues, and novel 3,6-disubstituted pyran derivatives | WAYNE STATE UNIVERSITY (US) | 2013-08-27 | — | — | US | disclosed |