Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487087 | 0.67 | KDM4E (0.35) | KDM4EALDH1A1GAAHPGDALOX12 | |
| Hydrochloric Acid SCHEMBL6741838 | 0.64 | KDM4E (0.33) | KDM4EALDH1A1GAAHPGDALOX12 | |
| SCHEMBL15201342 | 0.57 | — | — | |
| SCHEMBL8723351 | 0.54 | — | — | |
| SCHEMBL31288958 | 0.54 | — | — | |
| SCHEMBL5405661 | 0.54 | — | — | |
| SCHEMBL13139151 | 0.54 | — | — | |
| SCHEMBL8826943 | 0.50 | ADRA2C (0.42) | — | |
| SCHEMBL15337804 | 0.50 | KMT2A (0.65) | KDM4EGAA | |
| SCHEMBL15850760 | 0.48 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8648064-B2 | Metal complexes of N-heterocyclic carbenes | THE UNIVERSITY OF AKRON (US) | 2014-02-11 | — | — | US | disclosed |
| US-8519146-B2 | Purine or imidazole and silver complexes; therapeutic, antimicrobial, and antifungal compounds; urinary tract infections | THE UNIVERSITY OF AKRON (US) | 2013-08-27 | — | — | US | disclosed |