SCHEMBL15216239

SCHEMBL15216239

C=CC(=O)OCCN(C)S(=O)(=O)CCC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.50
HPGD P15428 1/20 0.50
ALDH1A1 P00352 5/20 0.42
TP53 P04637 3/20 0.42
HIF1A Q16665 3/20 0.42
CYP3A4 P08684 2/20 0.42
HSD17B10 Q99714 1/20 0.42
THRB P10828 3/20 0.40
ATM Q13315 1/20 0.33
HCAR2 Q8TDS4 2/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
DNM1 Q05193 1/20 0.31
ZDHHC20 Q5W0Z9 1/20 0.30
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
CHRM5 P08912 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRNB2 P17787 1/20 0.30
CHRM3 P20309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10760538 0.80 TSHR (0.49) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28569314 0.79 TSHR (0.46) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL14395654 0.78 TSHR (0.35) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL15216240 0.78 TSHR (0.47) TSHRALDH1A1THRBDNM1CHRM2
SCHEMBL2784609 0.77 TSHR (0.34) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL10766122 0.76 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28515730 0.76 TSHR (0.50) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL14066255 0.75 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL11310515 0.75 TSHR (0.58) TSHRHPGDALDH1A1TP53HIF1A
Sulfuric Acid SCHEMBL27667403 0.75 TSHR (0.48) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170322345-A1 HARDCOAT FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND METHOD FOR MANUFACTURING HARDCOAT FILM FUJIFILM CORPORATION (JP) 2017-11-09 US disclosed
US-9279913-B2 Antireflective film, polarizing plate, and image display device FUJIFILM CORPORATION (JP) 2016-03-08 US disclosed
US-8920889-B2 Optical film, polarizing plate, and image-forming display device FUJIFILM CORPORATION (JP) 2014-12-30 US disclosed
US-8889236-B2 2014-11-18 US disclosed
US-20130222910-A1 OPTICAL FILM, POLARIZING PLATE, AND IMAGE-FORMING DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2013-08-29 US disclosed
US-20100021694-A1 ANTIREFLECTIVE FILM, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2010-01-28 US disclosed