SCHEMBL15216240

SCHEMBL15216240

C=C(C)C(=O)OCCN(C)S(=O)(=O)CCC

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
THRB P10828 1/20 0.45
ALDH1A1 P00352 2/20 0.33
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
DNM1 Q05193 1/20 0.31
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
CHRM5 P08912 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRNB2 P17787 1/20 0.30
CHRM3 P20309 1/20 0.30
CHRNA4 P43681 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10777866 0.80 TSHR (0.46) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL14395651 0.78 THRB (0.34) TSHRTHRBHTT
SCHEMBL19799085 0.78 THRB (0.47) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL2793442 0.77 THRB (0.33) TSHRTHRB
SCHEMBL2796829 0.76 THRB (0.33) TSHRTHRB
Hydroxyl Radical SCHEMBL28262370 0.76 TSHR (0.55) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL28520553 0.76 THRB (0.49) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL24264553 0.75 THRB (0.41) TSHRTHRBALDH1A1POLBAPEX1
Sulfuric Acid SCHEMBL4972943 0.75 TSHR (0.55) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL12346273 0.75 TSHR (0.55) TSHRTHRBALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170322345-A1 HARDCOAT FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND METHOD FOR MANUFACTURING HARDCOAT FILM FUJIFILM CORPORATION (JP) 2017-11-09 US disclosed
US-9279913-B2 Antireflective film, polarizing plate, and image display device FUJIFILM CORPORATION (JP) 2016-03-08 US disclosed
US-8920889-B2 Optical film, polarizing plate, and image-forming display device FUJIFILM CORPORATION (JP) 2014-12-30 US disclosed
US-8889236-B2 2014-11-18 US disclosed
US-20130222910-A1 OPTICAL FILM, POLARIZING PLATE, AND IMAGE-FORMING DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2013-08-29 US disclosed
US-20100021694-A1 ANTIREFLECTIVE FILM, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2010-01-28 US disclosed