Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25196445 | 0.91 | TLR9 (0.46) | MAPTKMT2ALMNACYP1A2CYP3A4 | |
| SCHEMBL10046643 | 0.91 | TLR9 (0.46) | MAPTKMT2ALMNACYP1A2CYP3A4 | |
| SCHEMBL22107480 | 0.83 | MAPT (0.57) | MAPTKMT2ALMNACYP1A2CYP3A4 | |
| SCHEMBL15216644 | 0.83 | MAPT (0.60) | MAPTKMT2ALMNACYP1A2CYP3A4 | |
| SCHEMBL30384420 | 0.80 | KMT2A (0.51) | MAPTKMT2ALMNACYP1A2CYP3A4 | |
| SCHEMBL15218314 | 0.80 | KMT2A (0.51) | MAPTKMT2ALMNACYP1A2CYP3A4 | |
| SCHEMBL15218333 | 0.80 | TLR9 (0.46) | MAPTKMT2ALMNACYP1A2CYP3A4 | |
| SCHEMBL25196954 | 0.79 | MAPT (0.64) | MAPTKMT2ALMNACYP1A2CYP3A4 | |
| SCHEMBL15218447 | 0.79 | MAPT (0.55) | MAPTKMT2ALMNAMEN1MAPK1 | |
| SCHEMBL18960622 | 0.78 | MAPT (0.61) | MAPTKMT2ALMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8871976-B2 | Chalcone structure fluorescence dye for embryonic stem cell probe | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2014-10-28 | — | — | US | disclosed |
| US-20130224790-A1 | Chalcone Structure Fluorescence Dye For Embryonic Stem Cell Probe | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2013-08-29 | — | — | US | disclosed |