Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 2/20 | 0.35 |
| ▸ | GPR3 | P46089 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10035114 | 0.84 | MEN1 (0.53) | MEN1THRBRECQLBLMKMT2A | |
| SCHEMBL10035109 | 0.83 | MEN1 (0.55) | MEN1THRBRECQLBLMKMT2A | |
| SCHEMBL10013630 | 0.69 | P2RY6 (0.59) | MEN1THRBRECQLBLMKMT2A | |
| SCHEMBL14013309 | 0.69 | MEN1 (0.66) | MEN1THRBRECQLBLMKMT2A | |
| SCHEMBL12252414 | 0.69 | MEN1 (0.66) | MEN1THRBRECQLBLMKMT2A | |
| SCHEMBL16574888 | 0.68 | MEN1 (0.62) | MEN1THRBRECQLBLMKMT2A | |
| SCHEMBL21885517 | 0.68 | MEN1 (0.59) | MEN1THRBRECQLBLMKMT2A | |
| SCHEMBL24522770 | 0.68 | KCNA3 (0.45) | MEN1KMT2ATDP1L3MBTL1CA12 | |
| SCHEMBL15216730 | 0.67 | MEN1 (0.61) | MEN1THRBRECQLBLMKMT2A | |
| SCHEMBL21648627 | 0.67 | MEN1 (0.57) | MEN1THRBRECQLBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9651490-B2 | Amine-substituted tricyclic fluorescent dyes | ATTO-TEC GMBH (DE) | 2017-05-16 | — | — | US | disclosed |
| US-20130224871-A1 | Novel Amine-Substituted Tricyclic Fluorescent Dyes | ATTO-TEC GMBH (DE) | 2013-08-29 | — | — | US | disclosed |