Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | USP2 | O75604 | 3/20 | 0.49 |
| ▸ | APAF1 | O14727 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | GLA | P06280 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | CASP1 | P29466 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14013309 | 0.80 | MEN1 (0.66) | MEN1KMT2ATDP1BLMTHRB | |
| SCHEMBL14013308 | 0.80 | MEN1 (0.60) | MEN1KMT2ATDP1BLMTHRB | |
| SCHEMBL16574888 | 0.79 | MEN1 (0.62) | MEN1KMT2ATDP1BLMTHRB | |
| SCHEMBL27308727 | 0.78 | MEN1 (0.63) | MEN1KMT2ATDP1BLMTHRB | |
| SCHEMBL13018157 | 0.78 | MEN1 (0.63) | MEN1KMT2ATDP1BLMTHRB | |
| SCHEMBL14046582 | 0.76 | MEN1 (0.56) | MEN1KMT2ATDP1BLMTHRB | |
| SCHEMBL26213880 | 0.76 | MEN1 (0.71) | MEN1KMT2ATDP1BLMTHRB | |
| SCHEMBL10035109 | 0.76 | MEN1 (0.55) | MEN1KMT2ATDP1BLMTHRB | |
| SCHEMBL18680518 | 0.76 | MEN1 (0.58) | MEN1KMT2ATDP1BLMTHRB | |
| SCHEMBL13525202 | 0.76 | MEN1 (1.00) | MEN1KMT2ATDP1BLMTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9651490-B2 | Amine-substituted tricyclic fluorescent dyes | ATTO-TEC GMBH (DE) | 2017-05-16 | — | — | US | disclosed |
| US-9651490-B2 | Amine-substituted tricyclic fluorescent dyes | ATTO-TEC GMBH (DE) | 2017-05-16 | — | — | US | disclosed |
| EP-2630195-B1 | NEW AMINE-SUBSTITUTED TRICYCLIC FLUORESCENT DYES | ATTO TEC GMBH (DE) | 2016-08-17 | — | — | EP | disclosed |
| US-20130224871-A1 | Novel Amine-Substituted Tricyclic Fluorescent Dyes | ATTO-TEC GMBH (DE) | 2013-08-29 | — | — | US | disclosed |
| US-20130224871-A1 | Novel Amine-Substituted Tricyclic Fluorescent Dyes | ATTO-TEC GMBH (DE) | 2013-08-29 | — | — | US | disclosed |