Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ARG1 | P05089 | 1/20 | 0.30 |
| ▸ | ARG2 | P78540 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12161958 | 1.00 | ATM (0.34) | ATMTHRATHRBARG1ARG2 | |
| SCHEMBL24449794 | 1.00 | ATM (0.34) | ATMTHRATHRBARG1ARG2 | |
| SCHEMBL25962279 | 0.76 | — | — | |
| SCHEMBL22275172 | 0.74 | ATM (0.37) | ATM | |
| SCHEMBL24449845 | 0.74 | ATM (0.37) | ATM | |
| SCHEMBL10271208 | 0.74 | ATM (0.37) | ATM | |
| SCHEMBL15112734 | 0.73 | CHRNB2 (0.30) | — | |
| SCHEMBL26695755 | 0.72 | ATM (0.35) | ATMARG1ARG2 | |
| SCHEMBL17420119 | 0.71 | — | — | |
| SCHEMBL54811 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066659-B1 | SUBSTITUTED SULFONAMIDE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2013-08-28 | — | — | EP | disclosed |