Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.34 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11989428 | 0.95 | ALDH1A1 (0.43) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL4696869 | 0.93 | ALDH1A1 (0.41) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL12103952 | 0.89 | ALDH1A1 (0.33) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL21814401 | 0.89 | ALDH1A1 (0.30) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL14724365 | 0.86 | GLA (0.33) | ALDH1A1GLALMNAHSD17B10 | |
| SCHEMBL1747681 | 0.86 | SMN1; SMN2 (0.39) | ALDH1A1TSHRSMN1; SMN2GAAHTT | |
| SCHEMBL29842557 | 0.85 | ALDH1A1 (0.32) | ALDH1A1TSHRHSD17B10 | |
| SCHEMBL11989407 | 0.85 | ALDH1A1 (0.32) | ALDH1A1TSHRHSD17B10 | |
| SCHEMBL10052377 | 0.84 | ALDH1A1 (0.37) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL2147484 | 0.83 | KMT2A (0.31) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210214374-A1 | COMPOUNDS AND COMPOSITIONS FOR OCULAR DELIVERY | Graybug Vision, Inc. (US) | 2021-07-15 | — | — | US | disclosed |
| US-20210214374-A1 | COMPOUNDS AND COMPOSITIONS FOR OCULAR DELIVERY | Graybug Vision, Inc. (US) | 2021-07-15 | — | — | US | disclosed |
| WO-2020069353-A1 | COMPOUNDS AND COMPOSITIONS FOR OCULAR DELIVERY | Graybug Vision, Inc. (US) | 2020-04-02 | — | — | WO | disclosed |
| US-9896522-B2 | Solid phase fluorescence labeling reagents and uses thereof | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2018-02-20 | — | — | US | disclosed |
| US-9896522-B2 | Solid phase fluorescence labeling reagents and uses thereof | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2018-02-20 | — | — | US | disclosed |
| US-20130224870-A1 | FLUORESCENCE LABELING REAGENTS AND USES THEREOF | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2013-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210214374-A1 | COMPOUNDS AND COMPOSITIONS FOR OCULAR DELIVERY | KDR, RB1, PDE6C | ALDH1A1 2125/4885TSHR 1601/4885CHRM5 3676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.