SCHEMBL15218396

SCHEMBL15218396

Cc1ccc(C(=O)/C=C/c2ccc(N(C)CCO)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.65
MAOB P27338 8/20 0.58
MAOA P21397 4/20 0.58
RAB9A P51151 2/20 0.58
POLB P06746 2/20 0.58
CYP1B1 Q16678 3/20 0.56
ALDH1A1 P00352 2/20 0.56
CYP3A4 P08684 1/20 0.56
HPGD P15428 1/20 0.56
TLR9 Q9NR96 2/20 0.55
CRHBP P24387 1/20 0.55
CRHR2 Q13324 1/20 0.55
CYP1A1 P04798 1/20 0.53
KMT2A Q03164 2/20 0.52
NPC1 O15118 1/20 0.52
CASP3 P42574 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
SENP8 Q96LD8 1/20 0.52
SENP7 Q9BQF6 1/20 0.52
SENP6 Q9GZR1 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15218085 0.90 MAPT (0.52) MAPTMAOBMAOARAB9APOLB
SCHEMBL15216642 0.88 MAPT (0.56) MAPTMAOBRAB9APOLBCYP1B1
SCHEMBL25195905 0.88 MAPT (0.71) MAPTMAOBMAOARAB9APOLB
SCHEMBL25190663 0.88 MAPT (0.71) MAPTMAOBMAOARAB9APOLB
SCHEMBL25197170 0.88 MAOB (0.59) MAPTMAOBMAOARAB9ACYP1B1
SCHEMBL25194492 0.88 MAOB (0.59) MAPTMAOBMAOARAB9ACYP1B1
SCHEMBL25207425 0.88 MAPT (0.56) MAPTMAOBRAB9APOLBCYP1B1
SCHEMBL15218331 0.88 MAPT (0.61) MAPTMAOBRAB9APOLBCYP1B1
SCHEMBL25194276 0.88 MAPT (0.61) MAPTMAOBRAB9APOLBCYP1B1
SCHEMBL25194702 0.84 MAOB (0.63) MAPTMAOBMAOACYP1B1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed
US-8871976-B2 Chalcone structure fluorescence dye for embryonic stem cell probe NATIONAL UNIVERSITY OF SINGAPORE (SG) 2014-10-28 US disclosed
US-20130224790-A1 Chalcone Structure Fluorescence Dye For Embryonic Stem Cell Probe AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2013-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAPT 3297/4885MAOB 1004/4885MAOA 1902/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885MAOB 2435/4885MAOA 3145/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885MAOB 2435/4885MAOA 3145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.