Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | KIF11 | P52732 | 2/20 | 0.54 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.52 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.51 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | CA7 | P43166 | 3/20 | 0.51 |
| ▸ | CA9 | Q16790 | 3/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | CCR2 | P41597 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13145697 | 0.86 | HPGD (0.49) | MAPTKIF11CYP17A1EPHX2NR1H4 | |
| SCHEMBL3377569 | 0.86 | KIF11 (0.51) | KDRKMT2AMAPTTP53KIF11 | |
| SCHEMBL15220225 | 0.81 | CYP17A1 (0.60) | KIF11CYP17A1 | |
| SCHEMBL3375785 | 0.81 | KIF11 (0.59) | MAPTKIF11CYP17A1 | |
| SCHEMBL10804574 | 0.81 | MAPT (0.69) | KMT2AMAPTTP53CA1CA2 | |
| SCHEMBL527332 | 0.80 | KIF11 (0.54) | KMT2AMAPTKIF11CYP17A1CA1 | |
| SCHEMBL22060018 | 0.80 | KIF11 (0.57) | MAPTKIF11CYP17A1 | |
| SCHEMBL9390760 | 0.78 | HPGD (0.58) | KIF11CYP17A1EPHX2LMNA | |
| SCHEMBL31240769 | 0.78 | KIF11 (0.51) | KMT2AKIF11CYP17A1EPHX2NR1H4 | |
| SCHEMBL3932771 | 0.77 | KIF11 (0.50) | KMT2AMAPTKIF11CYP17A1RAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3323813-A1 | HISTONE ACETYLTRANSFERASE MODULATORS AND USES THEREOF | The Trustees of Columbia University in the City of New York (US) | 2018-05-23 | — | — | EP | disclosed |
| US-20170121276-A1 | HISTONE ACETYLTRANSFERASE MODULATORS AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-05-04 | — | — | US | disclosed |
| US-9274419-B2 | Blue photosensitive resin composition for color filter and application thereof | CHI MEI CORPORATION (TW) | 2016-03-01 | — | — | US | disclosed |
| US-20150268554-A1 | BLUE PHOTOSENSITIVE RESIN COMPOSITION FOR COLOR FILTER AND APPLICATION THEREOF | CHI MEI CORPORATION (TW) | 2015-09-24 | — | — | US | disclosed |
| US-9086532-B2 | Blue photosensitive resin composition for color filter and uses thereof | CHI MEI CORPORATION (TW) | 2015-07-21 | — | — | US | disclosed |
| US-9081142-B2 | Photosensitive resin composition for a color filter and uses thereof | CHI MEI CORPORATION (TW) | 2015-07-14 | — | — | US | disclosed |
| US-20150042931-A1 | BLUE PHOTOSENSITIVE RESIN COMPOSITION FOR COLOR FILTER AND USES THEREOF | CHI MEI CORPORATION (TW) | 2015-02-12 | — | — | US | disclosed |
| US-20140346416-A1 | PHOTOSENSITIVE RESIN COMPOSITION FOR A COLOR FILTER AND USES THEREOF | CHI MEI CORPORATION (TW) | 2014-11-27 | — | — | US | disclosed |
| US-20130222738-A1 | COLOR LIQUID CRYSTAL DISPLAY DEVICE | CHI MEI CORPORATION (TW) | 2013-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170121276-A1 | HISTONE ACETYLTRANSFERASE MODULATORS AND USES THEREOF | EP300, KAT2A, HTT | KDR 4841/4885KMT2A 51/4885MAPT 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.