Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 11/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.44 |
| ▸ | NEK2 | P51955 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13929775 | 0.86 | CYP2D6 (0.43) | CYP2D6SMN1; SMN2CYP2C19NEK2CYP2C9 | |
| SCHEMBL25723117 | 0.83 | CYP2D6 (0.44) | CYP2D6SMN1; SMN2CYP2C19NEK2CYP2C9 | |
| SCHEMBL18400630 | 0.78 | POLB (0.41) | CYP2D6SMN1; SMN2HSD17B10ALDH1A1TSHR | |
| SCHEMBL28546228 | 0.78 | CYP2D6 (0.41) | CYP2D6SMN1; SMN2CYP2C19NEK2CYP2C9 | |
| SCHEMBL25626550 | 0.78 | CYP2D6 (0.53) | CYP2D6SMN1; SMN2CYP2C19NEK2CYP2C9 | |
| SCHEMBL1025135 | 0.77 | CA1 (0.48) | CYP2D6SMN1; SMN2 | |
| SCHEMBL7603407 | 0.77 | CYP2D6 (0.47) | CYP2D6SMN1; SMN2CYP2C19NEK2CYP2C9 | |
| SCHEMBL9991833 | 0.77 | CNR1 (0.32) | CYP2D6SMN1; SMN2 | |
| SCHEMBL12895012 | 0.76 | CYP2D6 (0.56) | CYP2D6SMN1; SMN2CYP2C19NEK2CYP2C9 | |
| SCHEMBL17507855 | 0.76 | CYP2D6 (0.43) | CYP2D6SMN1; SMN2CYP2C19NEK2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4006028-A1 | IRAK4 KINASE INHIBITOR AND PREPARATION METHOD THEREFOR | Zhuhai Yufan Biotechnologies Co., Ltd (CN) | 2022-06-01 | — | — | EP | disclosed |
| US-20220119429-A1 | FLUORINE-CONTAINING COMPOUND AND ANTI-CANCER MEDICAL USE THEREOF | ASCENTAWITS PHARMACEUTICALS, LTD. (CN) | 2022-04-21 | — | — | US | disclosed |
| WO-2020228685-A9 | FLUORINE-CONTAINING COMPOUND AND ANTI-CANCER MEDICAL USE THEREOF | 深圳艾欣达伟医药科技有限公司 | 2021-02-18 | — | — | WO | disclosed |
| WO-2020228685-A1 | FLUORINE-CONTAINING COMPOUND AND ANTI-CANCER MEDICAL USE THEREOF | 深圳艾欣达伟医药科技有限公司 | 2020-11-19 | — | — | WO | disclosed |
| US-9867806-B2 | Compounds and pharmaceutical compositions thereof for the treatment of cystic fibrosis | GALAPAGOS NV (BE) | 2018-01-16 | — | — | US | disclosed |
| US-20160313639-A1 | PHOTOSENSITIVE RESIN COMPOSITION, PIXEL LAYER, PROTECTIVE FILM, SPACER, THIN-FILM TRANSISTOR, COLOR FILTER, AND LIQUID CRYSTAL DISPLAY APPARATUS | CHI MEI CORPORATION (TW) | 2016-10-27 | — | — | US | disclosed |
| EP-2671582-B1 | RING-FUSED HETEROCYCLIC DERIVATIVE | KYOWA HAKKO KIRIN CO LTD (JP) | 2016-07-13 | — | — | EP | disclosed |
| US-9274419-B2 | Blue photosensitive resin composition for color filter and application thereof | CHI MEI CORPORATION (TW) | 2016-03-01 | — | — | US | disclosed |
| US-20150268554-A1 | BLUE PHOTOSENSITIVE RESIN COMPOSITION FOR COLOR FILTER AND APPLICATION THEREOF | CHI MEI CORPORATION (TW) | 2015-09-24 | — | — | US | disclosed |
| US-9086532-B2 | Blue photosensitive resin composition for color filter and uses thereof | CHI MEI CORPORATION (TW) | 2015-07-21 | — | — | US | disclosed |
| US-9081142-B2 | Photosensitive resin composition for a color filter and uses thereof | CHI MEI CORPORATION (TW) | 2015-07-14 | — | — | US | disclosed |
| US-9000186-B2 | Ring-fused heterocyclic derivative | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2015-04-07 | — | — | US | disclosed |
| US-9000186-B2 | Ring-fused heterocyclic derivative | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2015-04-07 | — | — | US | disclosed |
| US-20150042931-A1 | BLUE PHOTOSENSITIVE RESIN COMPOSITION FOR COLOR FILTER AND USES THEREOF | CHI MEI CORPORATION (TW) | 2015-02-12 | — | — | US | disclosed |
| US-20150042931-A1 | BLUE PHOTOSENSITIVE RESIN COMPOSITION FOR COLOR FILTER AND USES THEREOF | CHI MEI CORPORATION (TW) | 2015-02-12 | — | — | US | disclosed |
| US-20140346416-A1 | PHOTOSENSITIVE RESIN COMPOSITION FOR A COLOR FILTER AND USES THEREOF | CHI MEI CORPORATION (TW) | 2014-11-27 | — | — | US | disclosed |
| US-20140346416-A1 | PHOTOSENSITIVE RESIN COMPOSITION FOR A COLOR FILTER AND USES THEREOF | CHI MEI CORPORATION (TW) | 2014-11-27 | — | — | US | disclosed |
| US-20140038941-A1 | RING-FUSED HETEROCYCLIC DERIVATIVE | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2014-02-06 | — | — | US | disclosed |
| US-20140038941-A1 | RING-FUSED HETEROCYCLIC DERIVATIVE | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2014-02-06 | — | — | US | disclosed |
| US-20130222738-A1 | COLOR LIQUID CRYSTAL DISPLAY DEVICE | CHI MEI CORPORATION (TW) | 2013-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220119429-A1 | FLUORINE-CONTAINING COMPOUND AND ANTI-CANCER MEDICAL USE THEREOF | FLI1, FOLR2, FOLR1 | CYP2D6 446/4885SMN1; SMN2 3609/4885CYP2C19 382/4885 |
| US-20140038941-A1 | RING-FUSED HETEROCYCLIC DERIVATIVE | CACNA1E, SLC8A1, CALCR | CYP2D6 2044/4885SMN1; SMN2 4334/4885CYP2C19 1422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.