Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F13A1 | P00488 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | TGM1 | P22735 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | WNT3A | P56704 | 2/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1620745 | 0.87 | EPHX2 (0.46) | F13A1TGM2TGM1MAPTWNT3A | |
| SCHEMBL1621211 | 0.77 | CNR2 (0.48) | NPC1FAAH | |
| SCHEMBL20281624 | 0.73 | ALOX5AP (0.45) | NPC1ALDH1A1MAPTMAPK1HTT | |
| SCHEMBL4013212 | 0.72 | EPHX2 (0.49) | F13A1TGM2TGM1MAPTWNT3A | |
| SCHEMBL1621137 | 0.72 | NPY5R (0.49) | NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL1621869 | 0.72 | CNR2 (0.46) | NPC1 | |
| SCHEMBL1619573 | 0.70 | NPY5R (0.47) | NPC1RAB9A | |
| SCHEMBL15219098 | 0.70 | RAB9A (0.44) | NPC1MAPTRAB9AKDM4E | |
| SCHEMBL1620749 | 0.70 | EPHX2 (0.47) | F13A1TGM2TGM1MAPTWNT3A | |
| SCHEMBL24738966 | 0.69 | GSK3B (0.43) | F13A1TGM2TGM1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074084-B1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2013-08-28 | — | — | EP | disclosed |