Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUAK1 | O60285 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | NEK2 | P51955 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | NEK6 | Q9HC98 | 1/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.44 |
| ▸ | IMPDH2 | P12268 | 17/20 | 0.38 |
| ▸ | IMPDH1 | P20839 | 8/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18401054 | 0.75 | NUAK1 (0.34) | NUAK1IGF1RMETPIM1SRC | |
| SCHEMBL75296 | 0.71 | KDM4E (0.44) | IMPDH2KDM4EALDH1A1LMNACYP1A2 | |
| SCHEMBL17842623 | 0.71 | POLB (0.42) | KDM4EALDH1A1CYP3A4HPGDHSD17B10 | |
| SCHEMBL14001892 | 0.70 | KMT2A (0.38) | NUAK1IGF1RMETPIM1SRC | |
| SCHEMBL17708233 | 0.70 | ALDH1A1 (0.42) | KDM4EALDH1A1CYP1A2HPGDSMN1; SMN2 | |
| SCHEMBL15388582 | 0.68 | POLB (0.41) | KDM4EALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL27986276 | 0.67 | ELANE (0.40) | KDM4EALDH1A1CYP1A2HPGDSMN1; SMN2 | |
| SCHEMBL38661155 | 0.67 | NUAK1 (0.54) | NUAK1IGF1RMETPIM1SRC | |
| SCHEMBL14173274 | 0.66 | ELANE (0.39) | SRCKDM4EALDH1A1CYP1A2HPGD | |
| SCHEMBL18676807 | 0.65 | HTT (0.31) | IMPDH2KDM4EALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2463714-B1 | Basic compound, chemically amplified resist composition and patterning process | SHINETSU CHEMICAL CO (JP) | 2013-08-28 | — | — | EP | disclosed |