Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24165648 | 0.92 | KDM4E (0.33) | KDM4EALDH1A1CA12CA2CA3 | |
| SCHEMBL19212955 | 0.88 | KDM4E (0.43) | KDM4EALDH1A1SIGMAR1CA12CA2 | |
| SCHEMBL14271449 | 0.88 | KDM4E (0.43) | KDM4EALDH1A1SIGMAR1CA12CA2 | |
| SCHEMBL21291699 | 0.86 | KDM4E (0.33) | KDM4EALDH1A1KCNH2HRH3 | |
| SCHEMBL14271429 | 0.86 | KDM4E (0.42) | KDM4EALDH1A1SIGMAR1CA12CA2 | |
| SCHEMBL6166961 | 0.85 | KDM4E (0.45) | KDM4EALDH1A1SIGMAR1CA12CA2 | |
| SCHEMBL10712412 | 0.85 | KCNH2 (0.37) | CA12CA2CA9KCNH2HTR2A | |
| SCHEMBL24362159 | 0.83 | KDM4E (0.41) | KDM4EALDH1A1SIGMAR1CA12CA2 | |
| SCHEMBL10714277 | 0.82 | KCNH2 (0.35) | KDM4ECA12CA2CA9KCNH2 | |
| SCHEMBL10713604 | 0.82 | KCNH2 (0.35) | KDM4EALDH1A1CA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3717466-B1 | COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I (CZ) | 2022-01-05 | — | — | EP | disclosed |
| US-9403860-B2 | Metathesis catalysts containing onium groups | APEIRON SYNTHESIS S.A. (PL) | 2016-08-02 | — | — | US | disclosed |
| US-9139609-B2 | C-4″ position substituted macrolide derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |
| US-20140046043-A1 | C-4\" POSITION SUBSTITUTED MACROLIDE DERIVATIVE | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2014-02-13 | — | — | US | disclosed |
| US-20130225807-A1 | Metathesis Catalysts Containing Onium Groups | APEIRON SYNTHESIS SP. ZO.O. (PL) | 2013-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140046043-A1 | C-4\" POSITION SUBSTITUTED MACROLIDE DERIVATIVE | MRPL21, MRPS34, MRPL37 | KDM4E 988/4885ALDH1A1 4667/4885SIGMAR1 3528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.